An international working party has conducted a study designed to select a suitable reference reagent for antihuman globulin, to replace those first made available in 1987. The chosen preparation contains levels of anti–IgG and anti–C3 (anti–C3c and anti–C3d) potency that are considered suitable to serve for reference when evaluating either polyspecific antihuman globulin reagents or those containing their separate monospecific components. The reference material is available in 2–ml freeze–dried aliquots from seven assigned distribution centres.

1.
Engelfriet CP, Voak D: International reference polyspecific antihuman globulin reagents. Vox Sang 1987;53:241–247.
2.
Löw B, Messeter L: Antiglobulin test in low–ionic strength salt solution for rapid antibody screening and cross–matching. Vox Sang 1974; 26:53–61.
1999
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