The first description of haemolytic diesase of the newborn due to anti-Duffy (anti-Fy^a) was published by Baker, Grewar, Lewis, Ayukawa, and Chown in 1956 [2], The following year Chown, Lewis, Kaita, and Greer [3] reported another example and pointed out that the anti-Fy^a serum used by Race, Sanger, and Lehane [11] in studying the antigen Fy^a had been obtained from a woman whose fourth child was born in 1951 with mild haemolytic disease. Race and Sanger [12] in 1954 and Mollison [10] in 1956 stated that the Duffy system had not as yet been implicated as a cause of erythroblastosis foetalis. It is our purpose to record another instance of haemolytic disease caused by anti-Fy^a and to present evidence indicating that it occurs more frequently than has been thought.

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