Depuis les travaux de Gurevitch et Nelken [4], ceux de Moureau et André [7], ceux de Dausset et Malinvaud [3], ceux de Maupin [5] et, plus récemment, ceux de Coombs et Bedford [1], il ne fait plus de doute que les plaquettes portent les antigènes A et B du système de groupe sanguin ABO. Mais il n’a jamais, encore, pu être mis en évidence la présence des antigènes des autres systèmes de groupes. En 1954, cependant, Darrigol [2] travaillant dans notre laboratoire, avait cru pouvoir constater une absorption significative des anticorps anti- D d’un sérum anti-Rh après contact avec une suspension concentrée de plaquettes issues d’un donneur D Positif. Le test de consommation d’antiglobuline, que nous avons mis au point en 1955 [6], devait nous permettre de reprendre cette étude. Nous rapporterons ici le résultat de nos recherches concernant l’antigène D, après avoir rappelé le principe de la réaction de consommation d’antiglobuline et précisé le méthode utilisée pour étudier les systèmes de groupes sur les plaquettes.

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