A hemoglobin variant with the slightly fast mobility associated with K hemoglobins was found, together with hemoglobin S, in an apparently healthy 3-year-old Negro girl from Washington, D.C. Her father had the same variant, along with hemoglobin A, and her mother had hemoglobins A + S. Respective proportions of hemoglobins K and S in the propositus were 66-34. The K variant now has been found to have the structural change Gln→Glu at position β131 (βH9) ; therefore it apparently is identical to hemoglobin Camden reported in trait form in a Negro subject by Yates, Bellingham and Huehns (Nature 243: 467-468, 1973).

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1975
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