Forty-four long-term red cell survival studies were performed in 39 patients,the majority of whom had either traumatic injuries or carcinoma. With the aid of a computer, the lifespan and the rate of random destruction of preserved red cells were estimated in each recipient. The 24-hour survival was a satisfactory measurement of the percent of viable red cells in the transfusion. The mean red cell lifespan (97 days) was not affected by either the method of preservation (liquid or freeze preservation) or the length of storage at+4 or — 80°C. Accelerated linear removal of red cells was seen in severely injured patients; improved red cell survival was associated with improvement in the recipient’s health. The correlation between the lifespan of transfused red cells and the recipient’s general health suggests that the decreased long-term survival noted in these recipients was produced by some extracorpuscular ‘toxic’ factor.

This content is only available via PDF.
1971
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.