...Lisa Sandmann; Benjamin Schulte; Michael P. Manns; Benjamin Maasoumy Background: Chronic hepatitis C virus (HCV) infection can lead to liver cirrhosis and its complications. Viral eradication is essential to prevent disease progression and reduces liver-related mortality and morbidity. Since...

..., instructions or products referred to in the content or advertisements. Hepatitis C virus Direct-acting antiviral agents Liver cirrhosis Sofosbuvir Hepatocellular carcinoma Chronic infection with the hepatitis C virus (HCV) is one of the most common causes of liver cirrhosis and its sequelae...

...Martin-Walter Welker; Stefan Zeuzem Summary Background: Hepatitis B virus (HBV)- and hepatitis C virus (HCV)-associated liver cirrhosis is a major indication for liver transplantation. This concise review gives an overview about current interferon (IFN)-free treatment options before and after liver...

..., while cirrhotics infected with hepatitis C virus (HCV) need to be prioritized for therapy with interferon (IFN)-free regimens. Antiviral therapy should be considered in HBV-infected patients with HCC, especially to prevent tumor recurrence after curative-intended therapy or to prevent hepatic...