...Oriol Juanola; Rubén Francés; Esther Caparrós Background: The global burden of liver disease and cirrhosis has been progressively increasing in the last decade. The interplay between gut microbiota and immune system and the bidirectional relationship with the liver, known as the gut-liver axis, has...

... for the presence of liver cirrhosis in multivariate analysis. In 17 patients, surgical treatment was cancelled due to major impairment of liver function. Only 4 out of 46 resected patients presented with post-hepatectomy liver failure (PHLF) grade ≥B. Histologic assessment revealed liver cirrhosis in 10 resected...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Portal hypertension Portal/mesenteric vein thrombosis Surgical portocaval shunt Cirrhosis Esophageal varices Portal hypertension (PH) is a frequent complication of liver...

...Beate Appenrodt; Frank Lammert Summary Renal failure is a severe complication in patients with liver cirrhosis. It is associated with increased mortality and morbidity. Diagnosis is a challenge because it is mainly based on serum creatinine, which does not seem to be an ideal measure of renal...

...Antonios Katsounas; Ali Canbay Summary Decompensated cirrhosis is characterized by high hospitalization rates and costs, frequent readmissions, and poor short-term survival. Patients admitted to the hospital with acute variceal bleeding and/or hepatic encephalopathy and/or renal dysfunction...

...Andreas Drolz; Arnulf Ferlitsch; Valentin Fuhrmann Summary Alterations in hemostasis are a characteristic feature of advanced liver disease. Patients with coagulopathy of advanced liver disease are prone to bleedings and also thromboembolic events. Under stable conditions, cirrhosis patients show...

..., HCV viral load, and HCV genotype. Ribavirin is required only for some treatment regimens and may be particularly beneficial in patients with cirrhosis. DAA resistance influences treatment outcome only marginally; thus, drug resistance testing is not routinely recommended before treatment. In the case...

... a high rate of complications and mortality due to intestinal infarction. Especially in patients with liver cirrhosis, special care is warranted with regard to PVTs due to their pathogenetic role and influence on patient survival. Conclusion: This article aims to summarize the current opinion...

... in the therapy of PH, we recommend a therapy strategy for the secondary prophylaxis of variceal bleeding in PH. Results: The main causes for PH in western countries are alcoholic/viral liver cirrhosis and extrahepatic portal/mesenteric vein occlusion, mainly caused by myeloproliferative neoplasms...

...Martin Rössle; Birke Bausch; Christoph Klinger Background: Treatment of non-malignant portal vein thrombosis (PVT) in patients with cirrhosis has been neglected in the past because of the fear of bleeding complications when using anticoagulation and due to the technical difficulties associated...

...Carlo Bartolozzi; Valentina Battaglia Background: Non-invasive diagnosis of hepatocellular carcinoma (HCC) in cirrhosis is nowadays the option of choice, as reported by both Western and Eastern guidelines. Methods: Currently, the diagnosis is still focused on the detection of the typical...