Background: Robot-assisted surgery aims to combine the advantages of open surgery with those of minimally invasive surgery to overcome the previous limitations of laparoscopy. Compared to conventional laparoscopic methods, robot-assisted techniques offer significant advantages, which are currently increasingly employed despite mostly longer operating times and higher costs. The aim of this review was to describe the current role of robotics in the treatment spectrum of colorectal surgery. Summary: A comprehensive literature review was conducted using PubMed, Medline, and Embase to identify studies, systematic reviews, and meta-analyses on robotic surgery for colorectal benign and malignant disease, focusing on studies and meta-analyses comparing the laparoscopic with the robotic approach; articles published between 2004 and 2024 were screened: results of studies on surgical techniques must always be interpreted with caution, taking into account the technical skills and preferences of the participating surgeons. Compared to conventional laparoscopic methods and independent of the indication, robot-assisted techniques offer obvious technical and ergonomic advantages. Most colorectal procedures can safely be conducted via robotic-assisted surgery. Throughout the various indications described in this manuscript, the most evident advantage of robotic surgery remains a lower conversion rate, followed by less blood loss and a shorter hospital stay at the price of a longer operating time. For malignant disease, robotic surgery seems to be additionally associated with a higher lymph node yield in the majority of the studies. In acute or chronic inflammatory colorectal diseases, robotic-assisted surgery may facilitate interventions through improved visibility and a potentially more precise dissection of the correct plane; furthermore, robotic-assisted surgery offers advantages for performing complex intracorporal anastomoses. Last but not least, the surgeon’s well-being and preferences make a relevant impact on the utilization of the system in colorectal surgery. Key Messages: The use of robot-assisted procedures has increased significantly in the last decade across the various surgical specialties, with the largest increase in colorectal surgery. Next to the surgeons’ preferences, capacity and costs will define the future role of robotic surgery in colorectal disease. As robotic surgery is becoming a mainstream surgical approach, there is a crying need for implementable training concepts of robotic techniques in colorectal surgery.

1.
Coccolini
F
,
Catena
F
,
Pisano
M
,
Gheza
F
,
Fagiuoli
S
,
Di Saverio
S
, et al
.
Open versus laparoscopic cholecystectomy in acute cholecystitis. Systematic review and meta-analysis
.
Int J Surg
.
2015
;
18
:
196
204
.
2.
Hung
CM
,
Hung
KC
,
Shi
HY
,
Su
SB
,
Lee
HM
,
Hsieh
MC
, et al
.
Medium-term surgical outcomes and health-related quality of life after laparoscopic vs open colorectal cancer resection: SF-36 health survey questionnaire
.
World J Gastrointest Endosc
.
2023
;
15
(
3
):
163
76
.
3.
Bonjer
HJ
,
Deijen
CL
,
Abis
GA
,
Cuesta
MA
,
van der Pas
MH
,
de Lange-de Klerk
ES
, et al
.
A randomized trial of laparoscopic versus open surgery for rectal cancer
.
N Engl J Med
.
2015
;
372
(
14
):
1324
32
.
4.
Lorenzon
L
,
Biondi
A
,
Carus
T
,
Dziki
A
,
Espin
E
,
Figueiredo
N
, et al
.
Achieving high quality standards in laparoscopic colon resection for cancer: a Delphi consensus-based position paper
.
Eur J Surg Oncol
.
2018
;
44
(
4
):
469
83
.
5.
Ferrari
D
,
Violante
T
,
Novelli
M
,
Starlinger
PP
,
Smoot
RL
,
Reisenauer
JS
, et al
.
The death of laparoscopy
.
Surg Endosc
.
2024
;
38
(
5
):
2677
88
.
6.
Zheng
J
,
Zhao
S
,
Chen
W
,
Zhang
M
,
Wu
J
.
Comparison of robotic right colectomy and laparoscopic right colectomy: a systematic review and meta-analysis
.
Tech Coloproctol
.
2023
;
27
(
7
):
521
35
.
7.
Waters
PS
,
Cheung
FP
,
Peacock
O
,
Heriot
AG
,
Warrier
SK
,
O’Riordain
DS
, et al
.
Successful patient-oriented surgical outcomes in robotic vs laparoscopic right hemicolectomy for cancer: a systematic review
.
Colorectal Dis
.
2020
;
22
(
5
):
488
99
.
8.
Wittmann
M
,
Vladimirov
M
,
Renz
M
,
Thumfart
L
,
Giulini
L
,
Dubecz
A
.
Robotische vs. laparoskopische Hemikolektomie rechts: eine Kostenanalyse [Robotic vs. laparoscopic right hemicolectomy-An analysis of costs]
.
Chirurgie
.
2024
;
95
(
8
):
651
5
. German.
9.
De’Angelis
N
,
Schena
CA
,
Espin-Basany
E
,
Piccoli
M
,
Alfieri
S
,
Aisoni
F
, et al
.
MERCY Study Collaborating Group Members. Robotic versus laparoscopic right colectomy for nonmetastatic pT4 colon cancer: a European multicentre propensity score-matched analysis
.
Colorectal Dis
.
2024
;
26
(
8
):
1569
83
.
10.
Rein
LKL
,
Dohrn
N
,
Gögenur
I
,
Falk Klein
M
.
Robotic versus laparoscopic approach for left-sided colon cancer: a nationwide cohort study
.
Colorectal Dis
.
2023
;
25
(
12
):
2366
77
.
11.
Zheng
H
,
Wang
Q
,
Fu
T
,
Wei
Z
,
Ye
J
,
Huang
B
, et al
.
Robotic versus laparoscopic left colectomy with complete mesocolic excision for left-sided colon cancer: a multicentre study with propensity score matching analysis
.
Tech Coloproctol
.
2023
;
27
(
7
):
559
68
.
12.
Emile
SH
,
Horesh
N
,
Freund
MR
,
Garoufalia
Z
,
Gefen
R
,
Silva-Alvarenga
E
, et al
.
Trends in the characteristics, treatment, and outcomes of rectal adenocarcinoma in the US from 2004 to 2019: a national cancer database analysis
.
JAMA Oncol
.
2023
;
9
(
3
):
355
64
.
13.
Jayne
D
,
Pigazzi
A
,
Marshall
H
,
Croft
J
,
Corrigan
N
,
Copeland
J
, et al
.
Effect of robotic-assisted vs conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: the ROLARR randomized clinical trial
.
JAMA
.
2017
;
318
(
16
):
1569
80
.
14.
Corrigan
N
,
Marshall
H
,
Croft
J
,
Copeland
J
,
Jayne
D
,
Brown
J
.
Exploring and adjusting for potential learning effects in ROLARR: a randomised controlled trial comparing robotic-assisted vs. standard laparoscopic surgery for rectal cancer resection
.
Trials
.
2018
;
19
(
1
):
339
.
15.
Stulberg
JJ
,
Huang
R
,
Kreutzer
L
,
Ban
K
,
Champagne
BJ
,
Steele
SR
, et al
.
Association between surgeon technical skills and patient outcomes
.
JAMA Surg
.
2020
;
155
(
10
):
960
8
.
16.
Feng
Q
,
Yuan
W
,
Li
T
,
Tang
B
,
Jia
B
,
Zhou
Y
, et al
.
Robotic versus laparoscopic surgery for middle and low rectal cancer (REAL): short-term outcomes of a multicentre randomised controlled trial
.
Lancet Gastroenterol Hepatol
.
2022
;
7
(
11
):
991
1004
.
17.
Slim
K
,
Tilmans
G
,
Occéan
BV
,
Dziri
C
,
Pereira
B
,
Canis
M
.
Meta-analysis of randomized clinical trials comparing robotic versus laparoscopic surgery for mid-low rectal cancers
.
J Visc Surg
.
2024
;
161
(
2
):
76
89
.
18.
Khan
MH
,
Tahir
A
,
Hussain
A
,
Monis
A
,
Zahid
S
,
Fatima
M
.
Outcomes of robotic versus laparoscopic-assisted surgery in patients with rectal cancer: a systematic review and meta-analysis
.
Langenbecks Arch Surg
.
2024
;
409
(
1
):
269
.
19.
Abdelsamad
A
,
Mohammed
MK
,
Serour
ASAS
,
Khalil
I
,
Wesh
ZM
,
Rashidi
L
, et al
.
Robotic-assisted versus laparoscopic-assisted extended mesorectal excision: a comprehensive meta-analysis and systematic review of perioperative and long-term outcomes
.
Surg Endosc
.
2024
;
38
(
11
):
6464
75
.
20.
O’Sullivan
NJ
,
Temperley
HC
,
Larkin
J
,
McCormick
JJ
,
Rausa
E
,
McCormick
P
, et al
.
Robotic transanal minimally invasive surgery (R-TAMIS): current evidence in the treatment of early rectal neoplasia
.
Int J Colorectal Dis
.
2024
;
39
(
1
):
71
.
21.
Flynn
J
,
Larach
JT
,
Kong
JCH
,
Warrier
SK
,
Heriot
A
.
Robotic versus laparoscopic ileal pouch-anal anastomosis (IPAA): a systematic review and meta-analysis
.
Int J Colorectal Dis
.
2021
;
36
(
7
):
1345
56
.
22.
Khawaja
Z
,
Jamal
Z
,
Zafar
N
,
Adnan
N
,
Haider
MI
,
Zafar
A
, et al
.
Role of robotic approach in ileal pouch-anal anastomosis (IPAA): a systematic review of the literature
.
J Robot Surg
.
2023
;
17
(
3
):
941
7
.
23.
Violante
T
,
Ferrari
D
,
Mathis
KL
,
Behm
KT
,
Shawki
SF
,
Dozois
EJ
, et al
.
Navigating progress: 8-year single-center experience with minimally invasive proctectomy and IPAA
.
Dis Colon Rectum
.
2024
;
67
(
11
):
1437
42
.
24.
Kühn
F
,
Nixdorf
M
,
Schwandner
F
,
Klar
E
.
Risk factors for early surgery and surgical complications in crohn’s disease
.
Zentralbl Chir
.
2018
;
143
(
06
):
596
602
. German.
25.
Calini
G
,
Abdalla
S
,
Abd El Aziz
MA
,
Saeed
HA
,
D’Angelo
ALD
,
Behm
KT
, et al
.
Intracorporeal versus extracorporeal anastomosis for robotic ileocolic resection in Crohn’s disease
.
J Robot Surg
.
2022
;
16
(
3
):
601
9
.
26.
Zaman
S
,
Mohamedahmed
AYY
,
Abdelrahman
W
,
Abdalla
HE
,
Wuheb
AA
,
Issa
MT
, et al
.
Minimally invasive surgery for inflammatory bowel disease: a systematic review and meta-analysis of robotic versus laparoscopic surgical techniques
.
J Crohns Colitis
.
2024
;
18
(
8
):
1342
55
.
27.
Larkins
K
,
Mohan
H
,
Apte
SS
,
Chen
V
,
Rajkomar
A
,
Larach
JT
, et al
.
A systematic review and meta-analysis of robotic resections for diverticular disease
.
Colorectal Dis
.
2022
;
24
(
10
):
1105
16
.
28.
Giuliani
G
,
Guerra
F
,
Coletta
D
,
Giuliani
A
,
Salvischiani
L
,
Tribuzi
A
, et al
.
Robotic versus conventional laparoscopic technique for the treatment of left-sided colonic diverticular disease: a systematic review with meta-analysis
.
Int J Colorectal Dis
.
2022
;
37
(
1
):
101
9
.
29.
Bistre-Varon
J
,
Gunter
R
,
Del Rio
RS
,
Elhadi
M
,
Gandhi
S
,
Robins
B
, et al
.
Is the NICE procedure the great equalizer for patients with high BMI undergoing resection for diverticulitis
.
Surg Endosc
.
2024
;
38
(
12
):
7518
24
.
30.
Chavrier
D
,
Alves
A
,
Menahem
B
.
Is laparoscopy a reliable alternative to laparotomy in Hartmann’s reversal? An updated meta-analysis
.
Tech Coloproctol
.
2022
;
26
(
4
):
239
52
.
31.
Barone
M
,
Ippoliti
M
,
Masetti
M
,
Mucilli
F
.
Robotic Hartmann’s reversal-feasibility and technical aspects
.
Updates Surg
.
2023
;
75
(
8
):
2391
4
.
32.
Giuliani
G
,
Formisano
G
,
Milone
M
,
Salaj
A
,
Salvischiani
L
,
Bianchi
PP
.
Full robotic Hartmann’s reversal: technical aspects and preliminary experience
.
Colorectal Dis
.
2020
;
22
(
11
):
1734
40
.
33.
De’Angelis
N
,
Felli
E
,
Azoulay
D
,
Brunetti
F
.
Robotic-assisted reversal of Hartmann's procedure for diverticulitis
.
J Robot Surg
.
2014
;
8
(
4
):
381
3
.
34.
Flynn
J
,
Larach
JT
,
Kong
JCH
,
Warrier
SK
,
Heriot
A
.
Robotic versus laparoscopic ventral mesh rectopexy: a systematic review and meta-analysis
.
Int J Colorectal Dis
.
2021
;
36
(
8
):
1621
31
.
35.
Wlodarczyk
J
,
Brabender
D
,
Gupta
A
,
Gaur
K
,
Madiedo
A
,
Lee
SW
, et al
.
Increased cost burden associated with robot-assisted rectopexy: do patient outcomes justify increased expenditure
.
Surg Endosc
.
2023
;
37
(
3
):
2119
26
.
36.
Singh
A
,
Kaur
M
,
Baig
MK
,
Swaminathan
C
,
Subramanian
A
,
Sajid
MS
.
Cost-comparison of robotic versus laparoscopic colorectal resections: a mapped systematic review and meta-analysis of published studies
.
Transl Gastroenterol Hepatol
.
2024
;
9
:
21
.
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