Introduction: Intussusception is a rare condition in adults. A pathological lesion is usually found with a significant percentage of malignancy. The optimal treatment is still not universally clear. Methods: This is a retrospective review of adult patients with a diagnosis of intestinal intussusception and surgically treated at our institution from January 2009 to December 2018. Clinical, operative, and histological details were collected and analyzed. Results: A total of 26 cases, 16 males and 10 females, were diagnosed with surgically proven intussusception during the 10-year period. The mean age was 45 years (range 21–70). Using ultrasound and/or computed tomography as imaging study, the preoperative diagnosis was made in 21/26 (81%) patients. Five intussusceptions were discovered only upon exploratory laparotomy for intestinal obstruction. There were 19 (73%) cases of enteric and 7 (27%) cases of colonic intussusceptions. All patients underwent surgical exploration. Intestinal resection with immediate anastomosis was the technique of choice for most patients. A single patient underwent stoma for peritonitis secondary to intestinal perforation. An organic cause has been systematically revealed, and no idiopathic intussusception was detected. Etiology was malignant in 9 (35%) cases. Conclusion: Adult intussusception should be considered in any patient with subacute abdominal pain. Considering the high rate of malignancy, intestinal resection without attempting reduction is highly recommended for colonic intussusceptions. However, a more selective approach can be adopted for enteric intussusceptions.

1.
de Moulin
D
.
Paul Barbette, M.D.: a seventeenth-century Amsterdam author of best-selling textbooks
.
Bull Hist Med
.
1985
;
59
(
4
):
506
14
.
[PubMed]
0007-5140
2.
Marsicovetere
P
,
Ivatury
SJ
,
White
B
,
Holubar
SD
.
Intestinal Intussusception: Etiology, Diagnosis, and Treatment
.
Clin Colon Rectal Surg
.
2017
Feb
;
30
(
1
):
30
9
.
[PubMed]
1531-0043
3.
Azar
T
,
Berger
DL
.
Adult intussusception
.
Ann Surg
.
1997
Aug
;
226
(
2
):
134
8
.
[PubMed]
0003-4932
4.
Gomes
A
,
Sousa
M
,
Pignatelli
N
,
Nunes
V
.
Adult intussusception: a single-center 10-year experience
.
Eur Surg
.
2013
Jan
;
45
(
5
):
239
44
. 1682-8631
5.
Traoré
D
,
Sissoko
F
,
Ongoïba
N
,
Traoré
I
,
Traoré
AK
,
Koumaré
AK
.
Adult intussusception: diagnostic pitfalls, morbidity and mortality in a developing country
.
J Visc Surg
.
2012
Jun
;
149
(
3
):
e211
4
.
[PubMed]
1878-7886
6.
Hong
KD
,
Kim
J
,
Ji
W
,
Wexner
SD
.
Adult intussusception: a systematic review and meta-analysis
.
Tech Coloproctol
.
2019
Apr
;
23
(
4
):
315
24
.
[PubMed]
1123-6337
7.
Ongom
PA
,
Opio
CK
,
Kijjambu
SC
.
Presentation, aetiology and treatment of adult intussusception in a tertiary Sub-Saharan hospital: a 10-year retrospective study
.
BMC Gastroenterol
.
2014
May
;
14
(
1
):
86
.
[PubMed]
1471-230X
8.
Zubaidi
A
,
Al-Saif
F
,
Silverman
R
.
Adult intussusception: a retrospective review
.
Dis Colon Rectum
.
2006
Oct
;
49
(
10
):
1546
51
.
[PubMed]
0012-3706
9.
Honjo
H
,
Mike
M
,
Kusanagi
H
,
Kano
N
.
Adult Intussusception: A Retrospective Review
.
World J Surg
.
2014
Sep
.
[PubMed]
0364-2313
10.
Kaval
S
,
Singhal
BM
,
Kumar
S
,
Singh
CP
.
Adult intussusception: an institutional experience and review of literature
.
Arch Int Surg.
2014
;
4
(
1
):
25
30
.
11.
Barussaud
M
,
Regenet
N
,
Briennon
X
,
de Kerviler
B
,
Pessaux
P
,
Kohneh-Sharhi
N
, et al.
Clinical spectrum and surgical approach of adult intussusceptions: a multicentric study
.
Int J Colorectal Dis
.
2006
Dec
;
21
(
8
):
834
9
.
[PubMed]
0179-1958
12.
Chang
CC
,
Chen
YY
,
Chen
YF
,
Lin
CN
,
Yen
HH
,
Lou
HY
.
Adult intussusception in Asians: clinical presentations, diagnosis, and treatment
.
J Gastroenterol Hepatol
.
2007
Nov
;
22
(
11
):
1767
71
.
[PubMed]
0815-9319
13.
Lindor
RA
,
Bellolio
MF
,
Sadosty
AT
,
Earnest
F
 4th
,
Cabrera
D
.
Adult intussusception: presentation, management, and outcomes of 148 patients
.
J Emerg Med
.
2012
Jul
;
43
(
1
):
1
6
.
[PubMed]
0736-4679
14.
Ciftci
F
.
Diagnosis and treatment of intestinal intussusception in adults: a rare experience for surgeons
.
Int J Clin Exp Med
.
2015
Jun
;
8
(
6
):
10001
5
.
[PubMed]
1940-5901
15.
Potts
J
,
Al Samaraee
A
,
El-Hakeem
A
.
Small bowel intussusception in adults
.
Ann R Coll Surg Engl
.
2014
Jan
;
96
(
1
):
11
4
.
[PubMed]
0035-8843
16.
Erkan
N
,
Haciyanli
M
,
Yildirim
M
,
Sayhan
H
,
Vardar
E
,
Polat
AF
.
Intussusception in adults: an unusual and challenging condition for surgeons
.
Int J Colorectal Dis
.
2005
Sep
;
20
(
5
):
452
6
.
[PubMed]
0179-1958
17.
Martín-Lorenzo
JG
,
Torralba-Martinez
A
,
Lirón-Ruiz
R
,
Flores-Pastor
B
,
Miguel-Perelló
J
,
Aguilar-Jimenez
J
, et al.
Intestinal invagination in adults: preoperative diagnosis and management
.
Int J Colorectal Dis
.
2004
Jan
;
19
(
1
):
68
72
.
[PubMed]
0179-1958
18.
Gupta
RK
,
Agrawal
CS
,
Yadav
R
,
Bajracharya
A
,
Sah
PL
.
Intussusception in adults: institutional review
.
Int J Surg
.
2011
;
9
(
1
):
91
5
.
[PubMed]
1743-9191
19.
Gupta
V
,
Doley
RP
,
Subramanya Bharathy
KG
,
Yadav
TD
,
Joshi
K
,
Kalra
N
, et al.
Adult intussusception in Northern India
.
Int J Surg
.
2011
;
9
(
4
):
297
301
.
[PubMed]
1743-9191
20.
Tan
KY
,
Tan
SM
,
Tan
AG
,
Chen
CY
,
Chng
HC
,
Hoe
MN
.
Adult intussusception: experience in Singapore
.
ANZ J Surg
.
2003
Dec
;
73
(
12
):
1044
7
.
[PubMed]
1445-1433
21.
Gayer
G
,
Zissin
R
,
Apter
S
,
Papa
M
,
Hertz
M
.
Pictorial review: adult intussusception—a CT diagnosis
.
Br J Radiol
.
2002
Feb
;
75
(
890
):
185
90
.
[PubMed]
0007-1285
22.
Yakan
S
,
Caliskan
C
,
Makay
O
,
Denecli
AG
,
Korkut
MA
.
Intussusception in adults: clinical characteristics, diagnosis and operative strategies
.
World J Gastroenterol
.
2009
Apr
;
15
(
16
):
1985
9
.
[PubMed]
1007-9327
23.
Amr
MA
,
Polites
SF
,
Alzghari
M
,
Onkendi
EO
,
Grotz
TE
,
Zielinski
MD
.
Intussusception in adults and the role of evolving computed tomography technology
.
Am J Surg
.
2015
Mar
;
209
(
3
):
580
3
.
[PubMed]
0002-9610
24.
Bar-Ziv
J
,
Solomon
A
.
Computed tomography in adult intussusception
.
Gastrointest Radiol
.
1991
;
16
(
3
):
264
6
.
[PubMed]
0364-2356
25.
Park
SB
,
Ha
HK
,
Kim
AY
,
Lee
SS
,
Kim
HJ
,
Park
BJ
, et al.
The diagnostic role of abdominal CT imaging findings in adults intussusception: focused on the vascular compromise
.
Eur J Radiol
.
2007
Jun
;
62
(
3
):
406
15
.
[PubMed]
0720-048X
26.
Kim
YH
,
Blake
MA
,
Harisinghani
MG
,
Archer-Arroyo
K
,
Hahn
PF
,
Pitman
MB
, et al.
Adult intestinal intussusception: CT appearances and identification of a causative lead point
.
Radiographics
.
2006
May-Jun
;
26
(
3
):
733
44
.
[PubMed]
0271-5333
27.
Tresoldi
S
,
Kim
YH
,
Blake
MA
,
Harisinghani
MG
,
Hahn
PF
,
Baker
SP
, et al.
Adult intestinal intussusception: can abdominal MDCT distinguish an intussusception caused by a lead point?
Abdom Imaging
.
2008
Sep-Oct
;
33
(
5
):
582
8
.
[PubMed]
0942-8925
28.
Boyle
MJ
,
Arkell
LJ
,
Williams
JT
.
Ultrasonic diagnosis of adult intussusception
.
Am J Gastroenterol
.
1993
Apr
;
88
(
4
):
617
8
.
[PubMed]
0002-9270
29.
Cerro
P
,
Magrini
L
,
Porcari
P
,
De Angelis
O
.
Sonographic diagnosis of intussusceptions in adults
.
Abdom Imaging
.
2000
Jan-Feb
;
25
(
1
):
45
7
.
[PubMed]
0942-8925
30.
Kim
D
,
Jung
H
,
Kim
M
,
Lee
J
,
Kim
S
,
Kang
D
, et al.
Endoscopic Treatment of Intussusception due to Intestinal Tuberculosis
.
Clin Endosc
.
2017
Mar
;
50
(
2
):
206
8
.
[PubMed]
2234-2400
31.
Wang
N
,
Cui
XY
,
Liu
Y
,
Long
J
,
Xu
YH
,
Guo
RX
, et al.
Adult intussusception: a retrospective review of 41 cases
.
World J Gastroenterol
.
2009
Jul
;
15
(
26
):
3303
8
.
[PubMed]
1007-9327
32.
Eisen
LK
,
Cunningham
JD
,
Aufses
AH
 Jr
.
Intussusception in adults: institutional review
.
J Am Coll Surg
.
1999
Apr
;
188
(
4
):
390
5
.
[PubMed]
1072-7515
33.
Ghaderi
H
,
Jafarian
A
,
Aminian
A
,
Mirjafari Daryasari
SA
.
Clinical presentations, diagnosis and treatment of adult intussusception, a 20 years survey
.
Int J Surg
.
2010
;
8
(
4
):
318
20
.
[PubMed]
1743-9191
34.
Ma
KW
,
Li
WH
,
Cheung
MT
.
Adult intussusception: A 15-year retrospective review
.
Surg Pract
.
2012
Feb
;
16
(
1
):
6
11
. 1744-1625
35.
Marinis
A
,
Yiallourou
A
,
Samanides
L
,
Dafnios
N
,
Anastasopoulos
G
,
Vassiliou
I
, et al.
Intussusception of the bowel in adults: a review
.
World J Gastroenterol
.
2009
Jan
;
15
(
4
):
407
11
.
[PubMed]
1007-9327
36.
Hanan
B
,
Diniz
TR
,
da Luz
MM
,
da Conceição
SA
,
da Silva
RG
,
Lacerda-Filho
A
.
Intussusception in adults: a retrospective study
.
Colorectal Dis
.
2010
Jun
;
12
(
6
):
574
8
.
[PubMed]
1462-8910
37.
Begos
DG
,
Sandor
A
,
Modlin
IM
.
The diagnosis and management of adult intussusception
.
Am J Surg
.
1997
Feb
;
173
(
2
):
88
94
.
[PubMed]
0002-9610
38.
Goh
BK
,
Quah
HM
,
Chow
PK
,
Tan
KY
,
Tay
KH
,
Eu
KW
, et al.
Predictive factors of malignancy in adults with intussusception
.
World J Surg
.
2006
Jul
;
30
(
7
):
1300
4
.
[PubMed]
0364-2313
39.
Kim
JW
,
Lee
BH
,
Park
SG
,
Kim
BC
,
Lee
S
,
Lee
SJ
.
Factors predicting malignancy in adult intussusception: an experience in university-affiliated hospitals
.
Asian J Surg
.
2018
Jan
;
41
(
1
):
92
7
.
[PubMed]
1015-9584
40.
Kim
KH
,
Namgung
H
,
Park
DG
.
Adult intussusceptions: preoperative predictive factors for malignant lead point
.
Ann Surg Treat Res
.
2014
May
;
86
(
5
):
244
8
.
[PubMed]
2288-6575
41.
El-Sergany
A
,
Darwish
A
,
Mehta
P
,
Mahmoud
A
.
Community teaching hospital surgical experience with adult intussusception: study of nine cases and literature review
.
Int J Surg Case Rep
.
2015
;
12
:
26
30
.
[PubMed]
2210-2612
42.
Yamada
H
,
Morita
T
,
Fujita
M
,
Miyasaka
Y
,
Senmaru
N
,
Oshikiri
T
.
Adult intussusception due to enteric neoplasms
.
Dig Dis Sci
.
2007
Mar
;
52
(
3
):
764
6
.
[PubMed]
0163-2116
43.
Gonda
TA
,
Khan
SU
,
Cheng
J
,
Lewis
SK
,
Rubin
M
,
Green
PH
.
Association of intussusception and celiac disease in adults
.
Dig Dis Sci
.
2010
Oct
;
55
(
10
):
2899
903
.
[PubMed]
0163-2116
44.
Shah
A
,
Roberts
J
,
Lipsky
H
,
Twersky
Y
,
Hirth
M
,
Chawla
K
.
Enteroenteric intussusception: an unusual presentation of Crohn’s disease in an adult patient
.
Am J Gastroenterol
.
1995
Dec
;
90
(
12
):
2231
2
.
[PubMed]
0002-9270
45.
Shenoy
S
.
Adult intussusception: A case series and review
.
World J Gastrointest Endosc
.
2017
May
;
9
(
5
):
220
7
.
[PubMed]
1948-5190
46.
Wang
LT
,
Wu
CC
,
Yu
JC
,
Hsiao
CW
,
Hsu
CC
,
Jao
SW
.
Clinical entity and treatment strategies for adult intussusceptions: 20 years’ experience
.
Dis Colon Rectum
.
2007
Nov
;
50
(
11
):
1941
9
.
[PubMed]
0012-3706
47.
Aydin
N
,
Roth
A
,
Misra
S
.
Surgical versus conservative management of adult intussusception: case series and review
.
Int J Surg Case Rep
.
2016
;
20
:
142
6
.
[PubMed]
2210-2612
48.
Onkendi
EO
,
Grotz
TE
,
Murray
JA
,
Donohue
JH
.
Adult intussusception in the last 25 years of modern imaging: is surgery still indicated?
J Gastrointest Surg
.
2011
Oct
;
15
(
10
):
1699
705
.
[PubMed]
1091-255X
49.
Lvoff
N
,
Breiman
RS
,
Coakley
FV
,
Lu
Y
,
Warren
RS
.
Distinguishing features of self-limiting adult small-bowel intussusception identified at CT
.
Radiology
.
2003
Apr
;
227
(
1
):
68
72
.
[PubMed]
0033-8419
50.
Mateen
MA
,
Saleem
S
,
Rao
PC
,
Gangadhar
V
,
Reddy
DN
.
Transient small bowel intussusceptions: ultrasound findings and clinical significance
.
Abdom Imaging
.
2006
Jul-Aug
;
31
(
4
):
410
6
.
[PubMed]
0942-8925
51.
Varban
OA
,
Ardestani
A
,
Azagury
DE
,
Kis
B
,
Brooks
DC
,
Tavakkoli
A
.
Contemporary management of adult intussusception: who needs a resection?
World J Surg
.
2013
Aug
;
37
(
8
):
1872
7
.
[PubMed]
0364-2313
52.
Greenley
CT
,
Ahmed
B
,
Friedman
L
,
Deitte
L
,
Awad
ZT
.
Laparoscopic management of sigmoidorectal intussusception
.
JSLS
.
2010
Jan-Mar
;
14
(
1
):
137
9
.
[PubMed]
1086-8089
53.
McKay
R
.
Ileocecal intussusception in an adult: the laparoscopic approach
.
JSLS
.
2006
Apr-Jun
;
10
(
2
):
250
3
.
[PubMed]
1086-8089
54.
Sundaram
B
,
Miller
CN
,
Cohan
RH
,
Schipper
MJ
,
Francis
IR
.
Can CT features be used to diagnose surgical adult bowel intussusceptions?
AJR Am J Roentgenol
.
2009
Aug
;
193
(
2
):
471
8
.
[PubMed]
0361-803X
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