Developmental mismatch model from Somerville et al. [2]. This schematic model illustrates the proposed developmental mismatch in brain maturation, with subcortical regions (such as the amygdala and NAcc/ventral striatum) maturing during adolescence, whereas the PFC does not reach a similar level of maturity until adulthood. The authors hypothesized the gap (shaded) in maturity would increase the risk for affectively driven behaviors during adolescence.