Analysis of the human and murine TMPRSS6 genes. a Alignment of the genomic organization of the human and murine TMPRSS6 genes. b Genomatix MatInspector predicted transcription factor motifs common in the proximal promoter regions of the human and murine TMPRSS6 genes. The genomic organization at the 5′ ends of the human and murine genes is not conserved. There is little to no sequence homology between the human and murine promoter and 5′-untranslated regions. Non-coding genomic coordinates are used (numbering from the ATG).