a DLBCL display variable cytomorphological characteristics, reflecting the variability in their biology and pathogenicity. Smears are in general highly cellular and display a more or less heterogeneous and polymorphic large cell population on a necrotic background with apoptotic bodies and macrophages with tingible bodies. Nuclear features are variable, including round or irregular nuclei and a variable number of nucleoli. H&E. ×600. b Immunophenotyping of DLBCL: T cells (yellow); large and abnormal B-cell population (red): CD20+, CD5-, CD10-, with light chain κ restriction. Colors refer to the online version only.