Distal pancreatectomy specimen from case 2 showing nests and trabeculae of tumor cells with round to oval nuclei, granular to vesicular chromatin, occasional prominent nucleoli, and moderate delicate to finely granular eosinophilic cytoplasm. Note focal acinar cell differentiation comprised of more prominent nucleoli, amphophilic cytoplasm, and coarse pink cytoplasmic granules (upper right). Hematoxylin and eosin stain. ×600.