Fig. 1
FNA of HPV-associated HNSCC with a basaloid pattern. a The aspirate is markedly cellular with a mixture of cohesive clusters of cells and loose aggregates of basaloid cells (Romanowsky stain, ×100). b The basaloid cells can exquisitely mimic small cell carcinoma with nuclear molding, mitoses, and single cell necrosis (Romanowsky stain, ×400). c A cystic component may be present with a mixed population of inflammatory cells, keratinized cells, and keratin debris (Romanowsky stain, ×400). d Adenoid cystic carcinoma-like areas may be present with acellular stromal spheres present that are surrounded by basaloid cells (Pap stain, ×200).

FNA of HPV-associated HNSCC with a basaloid pattern. a The aspirate is markedly cellular with a mixture of cohesive clusters of cells and loose aggregates of basaloid cells (Romanowsky stain, ×100). b The basaloid cells can exquisitely mimic small cell carcinoma with nuclear molding, mitoses, and single cell necrosis (Romanowsky stain, ×400). c A cystic component may be present with a mixed population of inflammatory cells, keratinized cells, and keratin debris (Romanowsky stain, ×400). d Adenoid cystic carcinoma-like areas may be present with acellular stromal spheres present that are surrounded by basaloid cells (Pap stain, ×200).

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