Measures can be applied to ensure the blood safety and supply during the pandemic. To ensure the blood safety, predonation health consultation, personal protection and environmental disinfection, blood donation appointment, feedback after blood donation, PRT, and delayed issuance of blood products can be used by blood collection agencies. To ensure the blood supply, strengthen blood inventory management, protect staff of blood collection agencies appropriately, and shorten delayed blood donation after vaccination can be used by blood collection agencies.