Histological diagnosis using D&C and cytological examination in a total of 142 evaluations of the therapeutic effect of MPA. Of 142 evaluations on the therapeutic effect of MPA using D&C, 76 had endometrial hyperplasia or worse, which were determined to be cases “with residual disease.” In the cytological evaluation performed concurrently, 51 cases had suspicious cytology or worse, while 91 cases had negative/inappropriate cytology. D&C, dilatation and curettage; MPA, medroxyprogesterone acetate.