Introduction: Urinary pleural effusion is a rare thoracic complication associated with urogenital diseases, primarily resulting from obstructive urinary tract disorders, but it can also arise from therapeutic or traumatic injuries. Due to its infrequency and the absence of clear diagnostic criteria, such cases are often overlooked. Case Presentation: In 3 reported cases, patients presented with typical symptoms such as dyspnea and chest pain. Following the diagnosis of urinary-derived pleural effusion, various treatment strategies were successfully implemented. All patients subsequently underwent surgery for urinary calculi during follow-up, without experiencing similar severe complications. Conclusion: Effective management of urinary-derived pleural effusion necessitates a multidisciplinary approach aimed at addressing the underlying urological issues. Once the urinary tract is treated, pleural effusion generally resolves quickly. These cases underscore the significance of early diagnosis and appropriate treatment, and clinicians should maintain a high index of suspicion for this condition to facilitate early diagnosis and individualized management.

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