Abstract
Introduction: Urinary tract paragangliomas account for less than 1% of all paragangliomas and are most commonly seen in the bladder, with the prostate being the second most common localization. However, urethral paragangliomas are extremely rare. Case Presentation: A 52-year-old male patient was admitted to the urology clinic with lower urinary tract symptoms (LUTS), including poor and intermittent stream, straining, frequency, and nocturia. A pedunculated polypoid lesion, approximately 1 cm in size, was detected at the level of the bulbar urethra and was excised from its stalk using cold cup forceps. A diagnosis of paraganglioma was made on histopathological examination. Conclusion: Anterior urethral paraganglioma can cause LUTS even if small due to urethral calibration. The recommended treatment method is endoscopic excision of the lesion. Paraganglioma should be kept in mind in the differential diagnosis of urethral lesions.
Journal Section:
Case Report
References
1.
Kantorovich
V
, Pacak
K
. Pheochromocytoma and paraganglioma
. Prog Brain Res
. 2010
;182
:343
–73
. 2.
Lee
JA
, Duh
Q-Y
. Sporadic paraganglioma
. World J Surg
. 2008
;32
(5
):683
–7
. 3.
Zhou
J
, Wu
W-F
, Zhang
W
, Xin
J
, Lei
W-H
. Successful transurethral resection of the prostate in ectopic prostate pheochromocytoma: a case report
. Medicine
. 2020
;99
(17
):e19852
. 4.
Zimmerman
IJ
, Biron
RE
, MacMahon
HE
. Pheochromocytoma of the urinary bladder
. N Engl J Med
. 1953
;249
(1
):25
–6
. 5.
Aksakallı
T
, Kozubaev
B
, Yapanoğlu
T
, Utlu
A
, Alper
F
, Bilen
A
, et al. Bladder paraganglioma treated with open partial cystectomy: a case report
. J Med Case Rep
. 2022
;16
(1
):479
. 6.
Hadj Kacem
F
, Boujelben
K
, Feki
W
, Chaabouni
K
, Charfi
N
, Abid
M
. Pheochromocytoma of the prostate: an unusual location
. Urol Case Rep
. 2022
;43
:102108
. 7.
Del Gaizo
A
, Silva
AC
, Lam-Himlin
DM
, Allen
BC
, Leyendecker
J
, Kawashima
A
. Magnetic resonance imaging of solid urethral and peri-urethral lesions
. Insights Imaging
. 2013
;4
(4
):461
–9
. 8.
Zhang
M
, Adeniran
AJ
, Vikram
R
, Tamboli
P
, Pettaway
C
, Bondaruk
J
, et al. Carcinoma of the urethra
. Hum Pathol
. 2018
;72
:35
–44
. 9.
Mira
JL
, Fan
G
. Leiomyoma of the male urethra: a case report and review of the literature
. Arch Pathol Lab Med
. 2000
;124
(2
):302
–3
. 10.
Silva
TA
, Perini
GM
, Gouvea
GV
, Marques
JEDA
, Beal
PR
, Col
LSD
, et al. Fibroepithelial polyp in the urethra: diagnostic challenges and endoscopic treatment outcomes
. Radiol Case Rep
. 2025
;20
(1
):374
–8
. 11.
Ishikawa
K
, Sasaki
H
, Shimoyama
H
, Yamagishi
M
, Sugishita
H
, Hashimoto
Y
, et al. Urethral hemangioma: how to investigate as a cause of hematuria after male sexual activities
. IJU Case Rep
. 2023
;6
(6
):454
–7
. 12.
Altavilla
G
, Cavazzini
L
, Russo
R
. Secreting benign paraganglioma of the prostatic urethra
. Tumori
. 1983
;69
(1
):79
–82
. 13.
Badalament
RA
, Kenworthy
P
, Pellegrini
A
, Drago
JR
. Paraganglioma of urethra
. Urology
. 1991
;38
(1
):76
–8
. 14.
Bryant
KR
, Thompson
IM
, Ortiz
R
, Spence
CR
. Urethral paraganglioma presenting as a urethral polyp
. J Urol
. 1983
;130
(3
):571
–2
. 15.
Chang
Y-K
, Chiang
I-N
, Chen
C-H
, Wang
S-M
, Lee
Y-J
, Pu
Y-S
, et al. Paragangliomas of the urinary bladder: a report of 6 cases and review of the literature
. Urol Sci
. 2015
;26
(2
):111
–4
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