Introduction: Using renography, we evaluated the function of both the kidneys and neobladder of 20 patients who underwent ileal bladder substitution. Methods: The patients were measured for renal and neobladder function with renography using 99mTc MAG3. Renal function was assayed in every renal unit using O’Reilly patterns. Voiding function was estimated using radioisotope counts for the reservoir. Results: Thirty-two of 37 renal units had normal renograms. Five renal units showed non-obstructive renograms. The percentage of total residual urine (RU) in the reservoir was 30% and more in 6 patients, 10–30% in 8, and <10% in 6. In 7 of 12 patients, the data on estimated RU correlated with the data on measured RU. However, in 5 patients, the data on estimated RU increased more in quantity than the data on RU measured at another time. Conclusions: In patients with bladder substitution the functions of both the kidneys and neobladder could be evaluated in a single renography.

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