Introduction and Objectives: Both computed tomography (CT) and renal scintigraphy (RS) have been used to assess vascular anatomy, renal status, and split renal function (SRF). In this study, we used a recently developed software that facilitates renal volumetric evaluations to compare RS and automated CT volumetry for assessing residual renal function and, thus, estimating postoperative renal function after donor nephrectomy. Methods: Fifty-one cases of donor nephrectomy were analyzed. Residual renal function was estimated based on RS and CT volumetry. The correlation between the postoperative estimated glomerular filtration rate (eGFR) and expected SRF, measured using RS and three types of CT volumetry data (ellipsoid, thin-slice, and 5-mm slice data), was determined. Results: The correlation coefficient between actual eGFR and expected SRF was significantly associated at each time point and modality (p < 0.0001). At any time point, the difference in correlation coefficient between RS and 5-mm volumetry was significant (p value: 0.003–0.018), whereas the differences in correlation coefficients between RS and the triaxial volume calculation, and the triaxial volume calculation and 5-mm volumetry, were generally statistically insignificant. Conclusions: Expected SRF was estimated more accurately by CT volumetric calculations (especially 5-mm slice-based volumetry) than RS.

1.
Oniscu
GC
,
Brown
H
,
Forsythe
JL
.
Impact of cadaveric renal transplantation on survival in patients listed for transplantation
.
J Am Soc Nephrol
.
2005
;
16
(
6
):
1859
65
.
2.
Yagisawa
T
,
Mieno
M
,
Ichimaru
N
,
Morita
K
,
Nakamura
M
,
Hotta
K
.
Trends of kidney transplantation in Japan in 2018: data from the kidney transplant registry
.
Ren Replace Ther
.
2019
;
5
(
1
):
3
.
3.
Yanishi
M
,
Kinoshita
H
,
Yoshida
T
,
Takayasu
K
,
Yoshida
K
,
Kawa
G
.
Comparison of renal scintigraphy and computed tomographic renal volumetry for determining split renal function and estimating post-transplant renal function
.
Transplant Proc
.
2015
;
47
(
9
):
2700
2
.
4.
Claisse
G
,
Gaillard
F
,
Mariat
C
.
Living kidney donor evaluation
.
Transplantation
.
2020
;
104
(
12
):
2487
96
.
5.
Delmonico
F
Council of the Transplantation Society
.
A report of the Amsterdam forum on the care of the live kidney donor: data and medical guidelines
.
Transplantation
.
2005
79
Suppl 2
S53
66
.
6.
Wesolowski
MJ
,
Conrad
GR
,
Šámal
M
,
Watson
G
,
Wanasundara
SN
,
Babyn
P
.
A simple method for determining split renal function from dynamic (99m)Tc-MAG3 scintigraphic data
.
Eur J Nucl Med Mol Imaging
.
2016
;
43
(
3
):
550
8
.
7.
Wehbi
E
,
Salle
A
,
Kanaroglou
N
,
Lorenzo
A
,
Bagli
D
,
Koyle
M
.
Measurement of differential renal function by scintigraphy in hydronephrotic kidneys: importance of conjugate views for accurate evaluation
.
J Urol
.
2016
;
195
(
2
):
471
5
.
8.
Banks
KP
,
Farrell
MB
,
Peacock
JG
,
Costello
M
,
Gordon
LL
.
Diuretic renal scintigraphy: the state of practice and a potential opportunity for standardization
.
J Am Coll Radiol
.
2021
;
18
(
11
):
1556
63
.
9.
Lange
D
,
Helck
A
,
Rominger
A
,
Crispin
A
,
Meiser
B
,
Werner
J
.
Renal volume assessed by magnetic resonance imaging volumetry correlates with renal function in living kidney donors pre- and postdonation: a retrospective cohort study
.
Transpl Int
.
2018
;
31
(
7
):
773
80
.
10.
Miyazaki
C
,
Harada
H
,
Shuke
N
,
Okizaki
A
,
Miura
M
,
Hirano
T
.
(99m)Tc-DTPA dynamic SPECT and CT volumetry for measuring split renal function in live kidney donors
.
Ann Nucl Med
.
2010
;
24
(
3
):
189
95
.
11.
Yokoyama
N
,
Ishimura
T
.
Usefulness of three-dimensional computerized tomographic volumetry for determining split renal function in donors for living-related kidney transplantation
.
Transplant Proc
.
2015
;
47
(
3
):
588
90
.
12.
Barbas
AS
,
Li
Y
,
Zair
M
,
Van
JA
,
Famure
O
,
Dib
MJ
.
CT volumetry is superior to nuclear renography for prediction of residual kidney function in living donors
.
Clin Transplant
.
2016
;
30
(
9
):
1028
35
.
13.
Mitsui
Y
,
Sadahira
T
,
Araki
M
,
Wada
K
,
Tanimoto
R
,
Ariyoshi
Y
.
The assessment of renal cortex and parenchymal volume using automated CT volumetry for predicting renal function after donor nephrectomy
.
Clin Exp Nephrol
.
2018
;
22
(
2
):
453
8
.
14.
Hua
L
,
Sebben
R
,
Olakkengil
S
,
Russell
C
,
Coates
T
,
Bhattacharjya
S
.
Correlation between computed tomography volumetry and nuclear medicine split renal function in live kidney donation: a single-centre experience
.
ANZ J Surg
.
2020
90
7–8
1347
51
.
15.
Matsuo
S
,
Imai
E
,
Horio
M
,
Yasuda
Y
,
Tomita
K
,
Nitta
K
.
Revised equations for estimated GFR from serum creatinine in Japan
.
Am J Kidney Dis
.
2009
;
53
(
6
):
982
92
.
16.
Meng
XL
,
Rosenthal
R
,
Rubin
DB
.
Comparing correlated correlation coefficients
.
Psychol Bull
.
1992
;
111
(
1
):
172
5
.
17.
Kanda
Y
.
Investigation of the freely available easy-to-use software “EZR” for medical statistics
.
Bone Marrow Transplant
.
2013
;
48
(
3
):
452
8
.
18.
Diedenhofen
B
,
Musch
J
.
Cocor: a comprehensive solution for the statistical comparison of correlations
.
PLoS One
.
2015
;
10
(
3
):
e0121945
.
19.
Dhull
RS
,
Joshi
A
,
Saha
A
.
Nuclear imaging in pediatric kidney diseases
.
Indian Pediatr
.
2018
;
55
(
7
):
591
7
.
20.
Janoff
DM
,
Davol
P
,
Hazzard
J
,
Lemmers
MJ
,
Paduch
DA
,
Barry
JM
.
Computerized tomography with 3-dimensional reconstruction for the evaluation of renal size and arterial anatomy in the living kidney donor
.
J Urol
.
2004
;
171
(
1
):
27
30
.
21.
El-Diasty
TA
,
Shokeir
AA
,
El-Ghar
ME
,
Gad
HM
,
Refaie
AF
,
El-Din
AB
.
Contrast enhanced spiral computerized tomography in live kidney donors: a single session for anatomical and functional assessment
.
J Urol
.
2004
;
171
(
1
):
31
4
.
22.
Luyckx
VA
,
Brenner
BM
.
The clinical importance of nephron mass
.
J Am Soc Nephrol
.
2010
;
21
(
6
):
898
910
.
You do not currently have access to this content.