The cystadenoma of the testis and paratestis arising from an unequivocal oviduct-like structure, which is morphologically almost identical with those of the ovarian surface epithelium. These are very rare benign tumors of young adults. They present as asymptomatic cystic lesions. Bilateral paratesticular cystadenomas are strongly associated with von Hippel-Lindau syndrome and correlate with infertility. It is a neoplasm with low malignant potential. Most cystadenomas are benign but a few cases of malignant transformation of embryonic remnants have been reported in the appendix testis, including cases of adenocarcinoma, cystadenocarcinoma, and a low malignant müllerian-type epithelial tumor. We report the rare case of a 63-year-old man with a paratesticular multicystic cystadenoma of the male adnexa without association to von Hippel-Lindau disease.

1.
Khoubehi B, Mishra V, Ali M, Motiwala H, Karim O: Adult paratesticular tumours. BJU Int 2002;90:707-715.
2.
Wernert N, Goebbels R, Prediger L: Papillary cystadenoma of the epididymis. Case report and review of the literature. Pathol Res Pract 1986;181:260-264.
3.
Krause W, Weidner W, Sperling H, Diemer T: Andrologie. Krankheiten der männlichen Geschlechtsorgane. Stuttgart, Thieme-Verlag, 2011.
4.
Amann K, Kain R, Koeppel G: Urogenitale und endokrine Organe, Gelenke und Skelett; in Kloeppel G, Kreipe HH, Remmele W (eds): Pathologie. Band 6, Springer-Verlag, 2016, pp 89-90.
5.
Nistal R, González-Peramato P, Serrano A, Vega-Perez M, De Miguel MP, Regadera J: Paratesticular cysts with benign epithelial proliferations of wolffian origin. Am J Clin Pathol 2005;124:245-251.
6.
Nogales FF, Goyenaga P, Preda O, Nicolae A, Vieites B, Ruiz-Marcellan MC, Pedrosa A, Merino MJ: An analysis of five clear cell papillary cystadenomas of mesosalpinx and broad ligament: four associated with von Hippel-Lindau disease and one aggressive sporadic type. Histopathology 2012;60:748-757.
7.
Ordi J, Nogales FF, Palacin A: Mesonephric adenocarcinoma of the uterine corpus: CD10 expression as evidence of mesonephric differentiation. Am J Surg Pathol 2001;25:1540-1545.
8.
Jones MA, Young RH, Srigley JR, Scully RE: Paratesticular serous papillary carcinoma. A report of six cases. Am J Surg Pathol 1995;19:1359-1365.
9.
Michal M, Kazakov DV, Kacerovska D, Kuroda N, Lovric E, Wachter DL, Agaimy A, Hes O: Paratesticular cystadenomas with ovarian stroma, metaplastic serous Müllerian epithelium, and male adnexal tumor of probable wolffian origin: a series of 5 hitherto poorly recognized testicular tumors. Ann Diagn Pathol 2013;17:151-158.
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