..., instructions or products referred to in the content or advertisements. 2025 Plasma Transfusion Fresh frozen plasma and plasma-derived clotting factors are cornerstones of the transfusion therapy to resolve dysbalances in coagulation. Early transfusion of plasma could reduce mortality...

...Zhi-Xiao Chen; Rong-Huo Liu; Jian-Cheng Huang; Jia-Min Mo; Yan-Qing Zeng; Yu-Chan Huang; Li-Ye Yang Objectives: This study aimed to evaluate the distribution of genotypes and iron metabolism imbalance in transfusion-dependent thalassemia patients. Methods: Genotype analysis was conducted on 84...

... hemoglobin, resulting in hemolysis, vasoocclusion, and multiorgan damage. While the pathophysiological cascade offers numerous targets for treatment, currently only two disease-modifying drugs have been approved in Europe and transfusion remains a mainstay of both preventing and treating severe complications...

... due to its high molecular specificity and sensitivity, which enable the study of cell viability, cell deformation, cell-protein, cell-nanoparticle, cell-cell interaction, etc. In transfusion medicine, RTS can give valuable insights into the storage lesions and effects of various preservatives...

...Gerd Klinkmann; Fanny Doss; Sandra Doss; Antje Schwarz; Susanne Reichert; Daniel A. Reuter; Kathleen Selleng; Thomas Thiele; Steffen Mitzner; Jens Altrichter Background: Granulocyte concentrates (GCs) are usually prepared by single-donor apheresis after G-CSF pretreatment and have to be transfused...

...Sven Arends; Michael Thomas; Michael Nosch; Thomas Droll; Denise Zwanziger; Thorsten Brenner; Ali Haddad Background: The use of cell salvage and autologous blood transfusion is an important and widespread method of blood conservation during surgeries with expected high blood loss. The continuous...

..., instructions or products referred to in the content or advertisements. 2023 COVID-19 convalescent plasma Blood donation Cytokines Transfusion Anti-SARS-CoV-2 antibodies Flow cytometry Due to the lack of therapies and the absence of specific antiviral medicines, COVID-19 convalescent plasma...

...) and its complex pathophysiology. Blood Transfus. 2022 Nov;20(6):443–5. 41. La Carpia F, Wojczyk BS, Annavajhala MK, Rebbaa A, Culp-Hill R, D’Alessandro A, et al. Transfusional iron overload and intravenous iron infusions modify the mouse gut microbiota similarly to dietary iron. NPJ Biofilms...

...Liron Miller; Mor Freed-Freundlich; Avichai Shimoni; Tamer Hellou; Abraham Avigdor; Mudi Misgav; Jonathan Canaani Introduction: Blood product transfusion retains a critical role in the supportive care of patients with acute myeloid leukemia (AML). Whereas previous studies have shown increased...

...Hyokee Kim; Sun-Young Ko; Jun Gyo Gwon Introduction: Recent guidelines recommend restrictive red blood cell transfusion; therefore, hospitals have started introducing and implementing patient blood management programs. This is the first study to analyze changes in the trends of blood transfusions...

...Johannes Raster; Michelle Jacob; Andreas Greinacher; Konstanze Aurich Background: Plasma transfusion is one of the basic treatments in patients with major blood loss. The anti-A and anti-B antibodies contained in the plasma demand ABO blood group compatibility. This is limiting the use of plasma...

..., instructions or products referred to in the content or advertisements. Trauma Resuscitation Whole blood Transfusion Plasma The only constant in life is change Heraclitus Dear Editor, That quotation is so true, is it not? Think back to when a physician was on call in the 1980s...

...Bryon P. Jackson; Jason L. Sperry; Mark H. Yazer Background: Early initiation of blood products transfusion after injury has been associated with improved patient outcomes following traumatic injury. The ability to transfuse patients’ plasma in the prehospital setting provides a prime opportunity...

...Florian Piekarski; Andrea Steinbicker; Kai Zacharowski; Patrick Meybohm Introduction: In recent years, resource-saving handling of allogeneic blood products and a reduction of transfusion rates in adults has been observed. However, comparable published national data for transfusion practices...

...Wei Zhang; Yan Zheng; Kun Yu; Juan Gu Objective: We aimed to determine whether the restrictive red-cell transfusion strategy was superior to the liberal one in reducing all-cause mortality in critically ill adults. Methods: The MEDLINE, EMBASE, PubMed, Web of Science, and Cochrane Library Central...

...Georg Stussi; Andreas Buser; Andreas Holbro Erythrocytapheresis, red blood cell (RBC) depletion, and RBC exchange transfusions are apheresis techniques used to rapidly lower the circulating RBC mass or to exchange the patient erythrocyte mass with donor RBC. Automated RBC exchange is performed...

... to release mediators that cause transfusion-associated lung injury (TRALI), a serious complication of transfusion. The HLA systems of both donor and patient are involved in transfusion-associated graft-versus-host disease, which is a rare disease with a high mortality. Patient HLA antibodies can destroy...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. B lymphocytes Transfusion...

...Ana Paula Hitomi Yokoyama; José Mauro Kutner; Araci Massami Sakashita; Cristiane Yoshie Nakazawa; Tatiana Almeida Omura de Paula; Raffael Perreira Cezar Zamper; Pamella Tung Pedroso; Marcio Dias de Almeida; Sergio Paiva Meira Filho; Fernanda Andrade Orsi Background: Transfusion of blood products...

...Wei Zhang; Kun Yu; Ni Chen; Miao Chen Objective: Whether the age of red blood cells (RBCs) affects mortality after transfusion in critically ill patients is controversial. Methods: We searched MEDLINE, EMBASE, PubMed, Web of Science, and the Cochrane Library Central Register of Controlled Trials...