... macrophage functions. Depending on the underlying pathology, platelets can enhance or diminish leukocyte cytokine production, indicating that platelet-leukocyte interactions represent a fine balanced system to restrict excessive inflammation during infection. In atherosclerosis, platelet interaction...

... to in the content or advertisements. Red blood cell storage Clinical outcome Inflammation Blood Transfusion Erythrocytes Pediatric cardiac surgery The storage age of red blood cells (RBCs) transfused often exceeds 5 days. Under storage, RBCs undergo alterations that affect their function...

... inflammation, and non-pathogen-induced tissue injury with ‘sterile’ tissue inflammation. In this review, evidence has been collected in support of the notion that the transfusion-related acute lung injury induces a ‘sterile’ inflammation in the lung of transfused patients in terms of an acute innate...

...Marleen Straat; Robin van Bruggen; Dirk de Korte; Nicole P. Juffermans Anemia is a frequently encountered problem in the critically ill patient. The inability to compensate for anemia includes several mechanisms, collectively referred to as anemia of inflammation: reduced production...