...Wolfgang Korte; Lukas Graf Summary Hemophilia is one of the best researched monogenic diseases. Hemophilia A will affect approximately 1:5,000 male live births. In recent decades, great progress has been made with the introduction of recombinant proteins in the 1990s for therapy and prophylaxis...

... may have clinical consequences for patients with hemophilia A. A human microvascular endothelial cell line (HMEC-1) [ 5 ] was cultured in endothelial cell medium (PAA, Cöbe, Germany) and supplemented with 2 mM L -glutamine, 100 IU/ml benzylpenicillin, and 100 mg/ml streptomycin. The human...

...-institutional, international consortium of early career hematology specialists in the field of hemophilia and other inherited bleeding disorders. The main objective of the group, whose members practice at institutions in North America, Europe, and South Africa, is to advance hemophilia care by providing a forum...

... was transmitted to individuals with hemophilia and frequent exposure to plasma-derived or recombinant clotting factors. Methods: We used highly sensitive real-time PCR to test plasma samples from 127 consecutive individuals with hemophilia who consulted our hemophilia center either for treatment or for a standard...

...Rolf Ljung; Marijke van den Berg; Leonard A. Valentino; Michael Manco-Johnson The International Network for Pediatric Hemophilia (INPH) comprises a group of physicians committed to the unique care of and challenges facing pediatric hemophilia patients. By collaborating on an international level...

... Activation and Complement ­Activation in Factor VIII and von Willebrand Factor ­Concentrates Martin F. Brodde Beate E. Kehrel Experimental und Clinical Hemostasis, Department of Anesthesiology and Intensive Care, University Hospital Muenster, Germany Keywords Factor VIII · Hemophilia · Leukocytes · Platelets...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hemophilia von Willebrand disease Type Normandy F VIII binding...