Background: The Fresenius AS 104® cell separator has recently met some popularity in European apheresis units for the quality of the platelets obtained with the totally automated double-needle procedure. Materials and Methods: Taking advantage of the machine’s flexibility we have developed a new automated procedure for single-needle thrombocytapheresis (SNP). So far 61 SNP were carried out. From donors having a platelet precount of 2.74 ×105 an average of 3.8 ×1011 cells were collected by processing 2.5 liters of blood in a run time of 83 min. Results and Conclusions: The leukocyte and erythrocyte contaminations were 2.7×107 and 3.5×107, respectively. Only 2 products did contain less than 3.5×1011 platelets, and 7 procedures were complicated by minor signs of hypocalcemia. With minor modifications this SNP is presently offered on a routine basis to our platelet donors.

Keywords:
Platelet concentrates, Single-needle apheresis, Plateletpheresis, Thrombocytapheresis, Donor apheresis, Platelet yield
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© 1993 S. Karger AG, Basel
1993
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