Regelmässig hämodialysierte Patienten (n = 29), konservativ-diätetisch behandelte UrämikerΔn = 41)undeinNormalkollektiv(n = 81 wurden mit Hilfe des Serumtransferrins auf ihren Eiweissernährungs-zustand untersucht. 80% der Dialysepatienten (Proteinzufuhr 1 g/ kg KG/die) und 20% der konservativ-diätetisch behandelten Ur-ämiepatienten (Proteinzufuhr 0,4 g/kg KG/die) zeigten pathologi-sche Transferrinwerte. Nach einer 12-wöchigen parenteralen Substitution der dialysebedingten Aminosäürenverluste wiesen 90% der Dialysepatienten wieder normale Transferrinwerte auf. Die in-fundierte Aminosäurenlösung (25 g in 250 ml) setzte sich vorwie-gend aus essentiellen L-Aminosäuren und L-Histidin zusammen.

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