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Keywords: MUC1
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Journal Articles
Journal Articles
Journal Articles
Subject Area:
Oncology
Tumor Biology (1994) 15 (6): 337–344.
Published Online: 30 April 2009
...Peter L. Devine; Michael A. McGuckin; Rachel J. Quin; Bruce G. Ward The serum MUC1 markers CASA and CA 15-3 were compared with CA 125 in the serum of patients with ovarian cancer and in pregnant women. Used individually, CASA and CA 15-3 gave sensitivities of 54 and 56% in pre-operative ovarian...
Journal Articles
Subject Area:
Oncology
Tumor Biology (1992) 13 (5-6): 268–277.
Published Online: 29 April 2009
..., LIM2412, LIM2463), as well as other colon (LS174T, HT29, HT29-SB, COL0533, COLO206), breast (T47D, MCF-7, BT20, ZR75–1) and ovarian (COLO316) tumor cell lines, was investigated. ELISA and Western blotting of the culture supernatants with novel anti-MUC1 and anti-MUC2 monoclonal antibodies (MAbs) specific...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2008) 28 (6): 312–317.
Published Online: 05 February 2008
...-specific markers for differentiating breast cancer from non-breast tissues. Expression of mammaglobin A (MGA), B726P, small breast epithelial mucin (SBEM) and MUC1 was measured by RT-PCR. MGA mRNA was detected in 86/162 (60%) breast cancers but in only 1/32 (3%) non-breast tissues; B726P was detected in 44...
Journal Articles
Journal Articles
Subject Area:
Oncology
Tumor Biology (2005) 26 (4): 217–220.
Published Online: 29 July 2005
...Uwe Karsten; Silvia von Mensdorff-Pouilly; Steffen Goletz The epithelial mucin 1 (MUC1) is an accepted serum tumor marker and cellular tumor antigen. We discuss recent views on the difference(s) between normal and tumor MUC1, and its implication for the development of cancer vaccines and antibody...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2003) 24 (4): 165–171.
Published Online: 08 December 2003
...P.D. Rye; K. Nustad; T. Stigbrand Since 1996, the nine ISOBM Workshops have so far characterized more than 300 monoclonal antibodies to a variety of tumor markers that include CA125, AFP, PSA, MUC1, Cytokeratins, Sialyl Le a , hCG, CEA, ALP, and more recently SCC, and S100. Besides the basic...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2003) 23 (6): 315–323.
Published Online: 04 April 2003
...Johan Bjerner; Lars F. Norum; Olle Nilsson; Kjell Nustad The aim of the study was to establish reference ranges and to explore the tumor specificities of two automated assays for MUC1. Sera from 124 female blood donors, 144 patients with benign disease of the breast, 69 patients with stage I, 75...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2001) 22 (4): 269–272.
Published Online: 01 June 2001
...Phil D. Rye; Michael A. McGuckin High molecular weight mucins represent a unique challenge as tumor markers by virtue of their complex array of epitopes. The list is dominated by the high molecular weight mucins MUC1, CEA and CA125. While the currently accepted role for these tumor markers...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2001) 22 (4): 216–222.
Published Online: 01 June 2001
..., with sensitivity ranging from 0.67 to 0.79, were below the top five experimental assays that showed sensitivity values between 0.79 and 0.85. The findings from our current study suggest that further development in MUC1 immunoassays could improve the detection of relapse in breast cancer patients. Research Article...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2001) 22 (4): 223–228.
Published Online: 01 June 2001
...Lars F. Norum; Bjørn Erikstein; Kjell Nustad The serum tumor markers CA 125, MUC1 and CEA were measured in 221 breast cancer patients over a period of 2 years. Patients examined on at least three occasions were included in the study. Thirty-three patients had increasing or continuously high...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2001) 22 (3): 169–175.
Published Online: 21 March 2001
...Lars F. Norum; Olle Nilsson; Kjell Nustad The aim of the present study was to establish a robust, reliable and fully automated immunofluorometric assay for the breast cancer serum marker MUC1. This would further serve as a prototype assay for evaluation of other MUC1 assays based on new antibody...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Oncology
Tumor Biology (1997) 19 (Suppl. 1): 30–34.
Published Online: 08 December 1997
...Shunsuke Imai; Satomi Haga; Yashuhiko Kiyozuka The 56 MAbs submitted to the ISOBM TD-4 Workshop were analysed by ELISA assay for reactivity against synthetic MUC1 mucin protein core-related peptides. With peptides comprising 5, 7 and 20 amino acids, 4/56 (7.1%), 33/56 (58.9%) and 51/56 (91.1...
Journal Articles
Subject Area:
Oncology
Tumor Biology (1997) 19 (Suppl. 1): 111–117.
Published Online: 08 December 1997
...Franz-Georg Hanisch The ISOBM TD-4 Workshop antibodies 122–177 were grouped according to their reactivity with: (a) monomeric MUC1 peptide (TAP25); (b) the pentameric tandem repeat peptide (TR-5), both unglycosylated or as their GalNAc-substituted derivatives, and (c) the lactation or tumor...
Journal Articles
Subject Area:
Oncology
Tumor Biology (1997) 19 (Suppl. 1): 46–56.
Published Online: 08 December 1997
...Andries Blockzjil; Karin Nilsson; Olle Nilsson The specificities of the 56 MAbs submitted to the ISOBM TD-4 Workshop were characterized by ELISA assays against MUC1-positive (ZR75-1) and MUC1-negative cell lines (LS174T), binding to a 20-mer peptide corresponding to the tandem repeat region of MUC1...
Journal Articles
Subject Area:
Oncology
Tumor Biology (1997) 19 (Suppl. 1): 118–121.
Published Online: 08 December 1997
... with MUC1 peptide or a carbohydrate specificity not represented. Two MAbs (127 and 128) detected Le x antigen and one MAb (157) reacted with A blood group. MAb 151 (and possibly 152) detected sialyl Tn epitopes. Three antibodies (139, 149 and 168) reacted with nonfucosylated structures (possibly LNT...