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Keywords: Class II transactivator
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Journal Articles
Subject Area:
Oncology
Journal:
Tumor Biology
Tumor Biology (2006) 28 (1): 27–35.
Published Online: 12 December 2006
... S100A4 promoter and demonstrate that IFN-γ represses S100A4 promoter activity through induction of the class II transactivator (CIITA). The acidic domain in the N-terminal part of CIITA was crucial for the observed IFN-γ-induced inhibition of S100A4 promoter activity, probably by binding the histone...