...S.S.T. Lo; D.K.L. Cheng; T.Y. Ng; L.C. Wong; H.Y.S. Ngan Serum cancer antigen (CA) 125, CA15.3, CA19.9, carcinoembryonic antigen and tissue polypeptide antigen were analyzed in 100 normal subjects, 47 patients with benign gynaecological diseases and 97 patients with endometrial cancer...

... of morphologically normal, but biologically altered epithelial cells. This aims of this study were to evaluate whether the expression of carcinoembryonic antigen (CEA) can act as a phenotypic marker of the field effect, and to map its topography in relation to the presence of colorectal adenocarcinoma...

... of 26,800 and 1,700 U/ml, respectively, p = 0.039 and 0.011). Also, the carcinoembryonic antigen (CEA) and tumour-associated trypsin inhibitor (TATI) levels in cyst fluid from mucinous tumours were much higher than those in non-mucinous tumours. Pre-treatment serum CA 195 levels were found to be elevated...

..., instructions or products referred to in the content or advertisements. Tumor markers Tumor antigen CA 27-19 CA 15-3 Mucin-like carcinoma antigen Carcinoembryonic antigen CA 19-9 Breast cancer Colon cancer Pancreas cancer Original Paper Tumor Biol 1994;15:247-254 Paul S. Frenettea Michael P...

...A. Bottini; A. Berruti; M. Tampellini; B. Morrica; A. Brunelli; E. Gnocchi; M.P. Brizzi; S. Aguggini; E. Fara; P. Alquati; L. Dogliotti Serum levels of CA 15–3, mucinous-like cancer antigen, carcinoembryonic antigen, tissue polypeptide antigen and tissue polypeptide-specific antigen (TPS) have been...

... was detected in patients with malignant liver disease, but high median values were also measured in patients with pancreatic cancer, bile duct cancer or benign liver disease. The sensitivity of TPS was 50.0%, with a specificity of 73% and an efficiency of 70%. In comparison with carcinoembryonic antigen (CEA...

...David M. Goldenberg This paper reviews the development of cancer imaging with radiolabeled antibodies to carcinoembryonic antigen and the current status and challenges for cancer therapy with radiolabeled antibodies. Advances in antibody preparations, choice of isotope and labeling methods, as well...

...Clifford P. Stanners; Luisa De Marte; Mercedes Rojas; Phil Gold; Abraham Fuks The human carcinoembryonic antigen (CEA) family can be divided into two subgroups according to the means of anchorage of member glycoproteins to the cell membrane: glycophos-phatidyl inositol (GPI) linkage...

...Y. Hinoda; M. Tsujisaki; K. Imai; A. Yachi Five anti-idiotypic (Id) monoclonal antibodies (MAbs) (Ab2) were prepared from a BALB/c mouse immunized with anti-carcinoembryonic antigen (CEA) MAb MA208 (Ab1) in a syngeneic system. These anti-Id MAbs appear to recognize unique idiotopes at the combining...

...John A. Thompson The carcinoembryonic antigen (CEA) gene family consists of approximately 30 genes, of which 17 are transcriptionally active. These genes are tightly clustered on the long arm of chromosome 19. Two main subgroups are distinguishable, one encoding CEA and its classical non-specific...

...Atsuo Nagata; Masakazu Miura; Tsugikazu Komoda A lectin-linked immunoradiometric assay (L-IRMA) using 7 different lectins and a monoclonal antibody (MoAb) directed against the protein moiety-specific epitope was developed to detect carcinoembryonic antigen (CEA). The method used for L-IRMA...

...Ole P. Börmer; Kari Thrane-Steen We have mapped the epitope group specificity of the monoclonal antibodies employed in six commercial sandwich immunometric assays for carcinoembryonic antigen (CEA), using cross-inhibition experiments with monoclonal antibodies previously classified...

...H. Biran; R. Feld; U. Sagman; J. Rusthoven; F.A. Shepherd; W.K. Evans; R.J. Ginsberg; T. Panzarella; A. Malkin Patients with small-cell lung cancer (SCLC) underwent serial blood monitoring during remission: 66 were tested for carcinoembryonic antigen (CEA) and calcitonin (CTN), including 40 who...

...Fairouz Zoubir; Jan Zeromski; Jan Sikora; Jan Szmeja; Anders Hedin; Sten Hammarström The tumor specificity of twelve different monoclonal antibodies (Mabs) against carcinoembryonic antigen (CEA) was assessed by immunohistochemistry. The Mabs had previously been classified into three specificity...

...Yuji Matsuoka; Yoshino Matsuo; Naomi Okamoto; Motomu Kuroki; Masahide Kuroki; Yukio Ikehara Carcinoembryonic antigen (CEA) was highly effectively extracted with phosphatidylinositol-specific phospholipase C (PI-PLC) from various source materials. The yield of CEA was, in some cases, 20–30 times...

...A.F. Pavlenko; A.V. Kurika; I.V. Chicalovets; Y.S. Ovodov Oncoprecipitins isolated from a number of marine invertebrates have been shown to be glycoproteins possessing a higher specificity to carcinoembryonic antigen (CEA) – similar to the interaction of antigen-antibody. The oncoprecipitin-CEA...

...A.F. Pavlenko; I.V. Chikalovets; A.V. Kurika; V.P. Glasunov; L.V. Mikhalyuk; Y.S. Ovodov The effects of temperature and pH on the spatial structure of carcinoembryonic antigen (CEA) and its various derivatives are studied by circular dichroic spectroscopy and differential UV spectroscopy...

...Kefung Chi; Milburn Jessup; Marsha L. Frazier We have analyzed specific transcripts of the carcinoembryonic antigen (CEA) gene family expressed in 32 colorectal carcinomas (CRCs) and when possible, their corresponding adjacent ( < 1 cm) and distant ( > 10 cm) mucosas. From 1 of the 32...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Carcinoembryonic antigen Monoclonal antibodies PhosphatidyUnositol anchor...

... to, yet distinct from carcinoembryonic antigen (CEA), and are termed ‘nonspecific cross-reacting antigens’ (NCAs). The NCA epitope recognized by the MAb 47D10 is expressed on the cell surface and has previously been shown to be distinct from epitopes detected by several anti-CEA MAbs, as well as by MAbs...