.... Methods: ProGRP, CEA, SCC, CA 125, CYFRA 21-1 and NSE were studied prospectively in 155 patients with unconfirmed suspicion of lung cancer and in 647 patients with lung cancer: 182 squamous, 205 adenocarcinomas, 19 large-cell lung cancer (LCLC), 175 small-cell lung cancer (SCLC) and 66 unspecific non...

... of the present study was to evaluate tumor marker variability in the follow-up of patients resected for breast cancer. So far, we have carried out 2,085 CEA and 2,550 CA 15-3 determinations in 435 patients. The total variability of both CEA and CA 15-3 was widely scattered among different subjects (CEA...

...X. Filella; R. Molina; J.M. Piqué; J.C. Garcia-Valdecasas; J.J. Grau; F. Novell; E. Astudillo; A. de Lacy; M. Daniels; A.M. Ballesta The serum levels of CA 19-9 were determined in the follow-up of 370 patients with colorectal cancer and compared with CEA. An increase in CA 19-9 preceded clinical...

...Antonio M. Ballesta; Rafael Molina; Xavier Filella; Judith Jo; Nuria Giménez The presence of a tumor antigen in human colonic carcinomas and their metastases was described about 25 years ago. This antigen, called carcinoembryonic antigen (CEA), is one of the first known tumor markers. Since...

...Christian Wittekind Following an analysis of the literature, the review concludes that the recent huge increase in our theoretical knowledge of the molecular biology of the CEA family has been accompanied by an adequate practical immunohistological implementation. However, a broader use of CEA...

... of substances similar to, yet distinct from carcinoembryonic antigen (CEA), and are termed nonspecific cross-reacting antigens (NCA). Formalin-fixed paraffin-embedded sections of colorectal adenocarcinomas were evaluated for the expression of these antigens and compared to the expression of CEA. Our study shows...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Breast Cancer CEA TPA CA 15–3 MCA Tumour markers Prognosis...

... lung carcinoma (SCLC) antigens, Fuc-GMl (fucosyl GM1; IV 2 FucII 3 NeuAc GgOse 4 ) and neural-cell adhesion molecule (NCAM), and two broader tumor antigens, carcinoembryonic antigen (CEA) and carbohydrate cancer-associated antigen CA 50. Expression of Fuc-GMl was seen in 75% and NCAM in 78% of the SCLC...

...Marius Nap; Kjeld Mollgard; Pierre Burtin; Gert Jan Fleuren This study concerns the immunohistologic distribution of carcino-embryonic antigen (CEA) in tissues and organs from 86 legal abortions, stillborn fetuses and perinatal deaths and from 5 adults without inflammatory disease or cancer...

...Florian Blankenburg; Rudolf Hatz; Dorothea Nagel; Donna Ankerst; Judith Reinmiedl; Christine Gruber; Dietrich Seidel; Petra Stieber Objective: To validate the prognostic value of preoperative levels of CYFRA 21-1, CEA and the corresponding tumor marker index (TMI) in patients with stage I non-small...

...Andreas Kremer; Stefan Holdenrieder; Petra Stieber; Ralf Wilkowski; Dorothea Nagel; Dietrich Seidel Apoptotic markers and tumor-associated antigens might be suitable to indicate the response to radiochemotherapy early. We analyzed the courses of nucleosomes, CEA, CA 19-9 and CYFRA 21-1 in 25...

...Monika Carpelan-Holmström; Johanna Louhimo; Ulf-Håkan Stenman; Henrik Alfthan; Heikki Järvinen; Caj Haglund Objective: The purpose of this study was to compare the utility of serum CEA, CA 19-9, CA 242, CA 72-4 and human chorionic gonadotropin (hCG)β in the follow-up of 102 surgically treated...

...P.D. Rye; K. Nustad; T. Stigbrand Since 1996, the nine ISOBM Workshops have so far characterized more than 300 monoclonal antibodies to a variety of tumor markers that include CA125, AFP, PSA, MUC1, Cytokeratins, Sialyl Le a , hCG, CEA, ALP, and more recently SCC, and S100. Besides the basic...

...R. Molina; X. Filella; J.M. Augé; R. Fuentes; I. Bover; J. Rifa; V. Moreno; E. Canals; N. Viñolas; A. Marquez; E. Barreiro; J. Borras; P. Viladiu CEA, CA 125, SCC, CYFRA 21-1 and NSE were prospectively studied in 211 patients with non-small cell lung cancer and compared with clinical parameters...

...Lars F. Norum; Bjørn Erikstein; Kjell Nustad The serum tumor markers CA 125, MUC1 and CEA were measured in 221 breast cancer patients over a period of 2 years. Patients examined on at least three occasions were included in the study. Thirty-three patients had increasing or continuously high...

... the in vitro production of IL-1β, IL-6 and TNF-α in whole-blood cell cultures of 10 healthy subjects after polyclonal activation with lipopolysaccharide of Salmonella enteridis and phytohemagglutinin in the presence or absence of three markers, AFP, CEA and PSA. Each sample was incubated for 48 h at 37°C...

...Lars Frängsmyr; Vladimir Baranov; Sten Hammarström To elucidate which of the seven transcriptionally active genes of the carcinoembryonic antigen (CEA) subfamily are expressed in human colon, we first examined mRNA expression using reverse transcriptase PCR. The result showed the CEA, nonspecific...

...A. van Dalen This study was designed to clinically evaluate four tumour markers on the automated chemiluminescent immunoanalyser, IMMULITE, and to compare the data obtained with those of established immunoassays. IMMULITE BR-MA and CEA were compared to the CIS ELSA CA 15-3 and either the CIS CEA...