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Keywords: Apoptosis
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Journal Articles
Subject Area:
Oncology
Tumor Biology (2009) 30 (3): 160–170.
Published Online: 16 July 2009
... controls revealed significant differences in the expression levels of 49 genes. Gene ontology identified an association of significantly up-/downregulated genes to six functional classes, particularly genes involved in apoptosis control such as LGALS1, LGALS3, BAX, IL7R and TNFRSF25. In RCC patients...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2009) 30 (3): 141–147.
Published Online: 15 June 2009
...J.F. McEwan; M.L. Windsor; S.D. Cullis-Hill A putative role for prion protein (PrP) in apoptosis has been implicated. This function was investigated to test whether antibodies to PrP could induce apoptosis and be utilised in the treatment of cancers. Various antibodies to PrP were screened in MTT...
Journal Articles
Journal Articles
Subject Area:
Oncology
Tumor Biology (1994) 15 (6): 345–353.
Published Online: 30 April 2009
...Riikka Huovinen; Yrjö Collan The antiestrogen toremifene treatment results in regression or stabilization of dimethylbenz(a)anthracene(DMBA)-induced rat mammary tumors by reducing the mitotic activity and possibly by modifying the abundant spontaneous apoptosis seen in these tumors. A comparative...
Journal Articles
Subject Area:
Oncology
Tumor Biology (1996) 17 (6): 354–361.
Published Online: 30 April 2009
...G. Basha; P. Yap; F. Penninckx The trypan blue exclusion test, the MTT test and an immuno-staining test for apoptosis were performed before and after incubation of SW620 human colonic carcinoma cells with different cytotoxic agents (CTAs) in order to assess tumor cell viability and CTA efficacy...
Journal Articles
Subject Area:
Oncology
Tumor Biology (1997) 18 (5): 261–273.
Published Online: 30 April 2009
... to precede other signs of cell death for several hours. Typical morphological changes of apoptosis were observed after 4 h of exposure of cells to high AFP doses. Low concentrations of cAFP and eAFP (less than 0.1 mg/ml) failed to induce growth inhibition of HepG2 cells, rather showing a weak stimulative...
Journal Articles
Subject Area:
Oncology
Tumor Biology (1997) 18 (3): 135–145.
Published Online: 30 April 2009
... Apoptosis Necrosis 10 04 1996 10 10 1996 30 4 2009 © 1997 S. Karger AG, Basel 1997 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means...
Journal Articles
Subject Area:
Oncology
Tumor Biology (1997) 18 (3): 146–156.
Published Online: 30 April 2009
...Nicholas Hawkins; Jacqueline Lees; Rebecca Hargrove; Terence O’Connor; Alan Meagher; Robyn Ward Purpose: Apoptosis is commonly observed in a variety of human tumors, and some of the genetic events which control this process have been identified in vitro. The aim of this study was to determine...
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Oncology
Tumor Biology (2008) 29 (5): 287–303.
Published Online: 19 September 2008
..., cell cycle, apoptosis and expression of cell-cycle- and apoptosis-regulatory genes were evaluated. Results: After treatment withc-myc AS[S]ODNs, the growth of cancer cells was markedly inhibited in a dose- and time-dependent manner and the levels of c-myc mRNA and protein were greatly decreased (p...
Journal Articles
Journal Articles
Subject Area:
Oncology
Tumor Biology (2008) 29 (2): 122–129.
Published Online: 11 June 2008
.... Methods: MS1 (a mouse endothelial cell line) was infected with an adenoviral vector ZD55-XAF1. Controls were uninfected or infected with ZD55-EGFP. Wound healing assay and tube formation assay were used to assess angiogenesis. Cell proliferation was detected by WST-1 assay, and apoptosis was detected...
Journal Articles
Journal Articles
Subject Area:
Oncology
Tumor Biology (2008) 29 (1): 57–62.
Published Online: 23 May 2008
.... Circulating CK-related polypeptides have commonly been used as tumor markers. While apoptosis is a mechanism of CK release, the molecular nature of circulating CKs is poorly understood. The aim is to clarify the dynamics of CK8 during apoptosis in vitro and the nature of circulating CK8 in patients with lung...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2008) 28 (6): 301–311.
Published Online: 05 February 2008
... was to determine the differential effects of the redox state and kinetics of nitrosative species on the key cancer processes of apoptosis. Therefore, a murine lung adenocarcinoma cell line was exposed to various NO X donor compounds differing in redox state and delivery kinetics. DNA strand breaks (DSBs) were...
Journal Articles
Subject Area:
Oncology
Tumor Biology (2007) 28 (4): 189–195.
Published Online: 23 August 2007
... present in the circulation of cancer patients are released from apoptotic or necrotic tumour cells. CK18 is cleaved by caspases during apoptosis and a monoclonal antibody (M30) specific to caspase-cleaved forms is available. The molecular form of CK18 released from cells (caspase-cleaved or not) can...
Journal Articles
Journal Articles
Journal Articles