..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2022 Disorders of sex development DSD Advocacy Education Intersex...

.... Congenital adrenal hyperplasia Disorders of sexual development Intersex Surgery Congenital adrenal hyperplasia (CAH) is the most common diagnosis in infants with virilization, 46,XX DSD. The incidence of classic virilising CAH is about 1:15,000 in most populations in the world [Speiser et al...

.... Clinical assessment Intersex Limitations Methodological issues Psychological evaluation Differences/disorders of sex development (DSD; also called “intersex conditions”) refers to a group of conditions in which chromosomal, gonadal, or anatomical sex is atypical. Classification is based...

.... Copy number variation FISH Intersex Masculinization Sex reversal SRY Virilization Disorder of sex development Dog Testicular or ovotesticular disorder of sex development (DSD) in individuals with a female karyotype and a lack of the Y-linked SRY gene have been diagnosed in numerous...

.... Intersex Male Karyotype Testis Tomcat Sex chromosome DSD SRY Normal sexual development in mammals is a multi-step process that includes the establishment of chromosomal, gonadal, and phenotypic sex. Impairment in any of these pathways leads to abnormal sexual development [Lyle, 2007; Meyers...

... noted that 2 intersex phenotypes occur in males of the amphipod Echinogammarus marinus , an external phenotype, in which males possess rudimentary brood plates, and an internal phenotype, in which only an ovotestis is present. This study examines the relationship between these phenotypes and finds...

..., instructions or products referred to in the content or advertisements. Aromatase European eel Hermaphrodite Intersex Genetic sex determination has been suggested in the 3 major species of temperate eels, i.e. Anguilla anguilla , A. rostrata and A. japonica , as in these species a pair...

..., instructions or products referred to in the content or advertisements. Androgen insensitivity Androgen receptor GTG start codon Horse Intersex SRY  + DSD syndrome Testicular feminization X chromosome Genetic sex in mammals is determined by the sex chromosomes of the zygote, which...

...G.F. Mastromonaco; M.L. Houck; D.R. Bergfelt Disorders of sexual development (DSDs) are an increasing concern in both captive and free-ranging wildlife species. Partial or complete reduction in fertility that results from intersex conditions or gonadal dysgenesis is detrimental to the reproductive...

...P.J. Das; S.K. Lyle; D. Beehan; B.P. Chowdhary; T. Raudsepp Sex chromosome aberrations commonly lead to abnormal sexual development. Here we cytogenetically and molecularly characterized Y isochromosome in an intersex horse. Blood lymphocyte analysis showed a mosaic karyotype with 96% 63,XO and 4...

... of these malformations increases the likelihood that the child will be investigated. Approach Disorder of sexual development Intersex Investigations Although the birth prevalence of complex anomalies that may lead to true genital ambiguity may be around 1:5,000 births [Thyen et al., 2006], overall...

...C. Wiesemann The clinical management of intersex has undergone a significant change in values. Whereas in former times, benevolent medical paternalism was the rule, today, the patient’s right to respect for dignity and self-determination is given priority. This paper discusses ethical...

...M.L. Cull; M. Simmonds Taboo still surrounds intersex/disorders of sex development, in spite of more openness in society regarding sex. Peer support is valuable in providing information and emotional support to those affected. Support groups also work with clinicians to promote better care...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Database Intersex Network Suspected cases of a disorder of sex...

... induced intersex individuals (presence of testicular oocytes). FAD treatment resulted in 55% male, 30% female and 15% intersex, while FIN treatment produced 27% male, 53% female and 20% intersex. Real-time RT-PCR analysis of hepatic sex steroid- and thyroid hormone-related gene expression demonstrated...

... this effect. The term Disorders of Sex Development (DSD) was proposed to replace the word intersex and is used to broaden previous classifications of congenital conditions in which development of chromosomal, gonadal or anatomical sex are inconsistent. DSDs involve those with ambiguous genitalia as well...

... discernible as a heterochromatic body which grows with increasing degree of polyploidy in somatic cells. It is used as a marker for the genetic sex in studies of intersexes and Wolbachia infections. The sex chromosome system is being exploited in economically important species. Special strains have been...

... insensitivity Gonadal dysgenesis Hermaphroditism Intersex Male pseudohermaphroditism Boy or girl? This is certainly the most common question asked when a child is born. Its answer, coming naturally and easily in the vast majority of cases, carries innocently a mark for the future of the newborn...

... Intersex NT2/D1 Sex determination SRY Sex determination in mammals is chromosomally controlled and governs whether a testis or an ovary forms in the embryo. The discovery of the testis-determining gene SRY on the Y chromosome gave an entry point into this molecular pathway [Gubbay et al., 1990...