...-fold increase in [ 3 H]ROH accumulation and an 80% decrease in [ 3 H]ddROH. Addition of synthetic retinoids with a terminal carboxyl (CD270, CD271, CD367 and Ro 13-7410) decreased the [ 3 H]ddROH accumulation with about 70%, but hardly at all affected the accumulation of [ 3 H]ROH. We conclude...

...Hans Törmä; Eva Stenström; Eva Andersson; Anders Vahlquist For unknown reasons, the epidermal concentrations of retinol and its metabolite 3,4-didehydroretinol become characteristically changed during treatment with certain synthetic retinoids. In the present study we investigated [ 3 H]retinol...