.... PKEK Peptide Skin permeation FTIR-ATR diffusion cell Stratum corneum Pig isolated stratum corneum Stratum corneum equivalents Shed snake skin In humans, the skin is the largest organ after the skeletal musculature, with a size of approximately 1.7 m 2 and a weight of 5 kg [ 1-3...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Microneedles Topical anaesthetic Tetracaine Skin permeation Venous access procedures are some of the most...

... prepared. In vitro release and skin permeation studies through human epidermis and full-thickness skin were performed by Franz diffusion cells. Results: The overall results highlighted that PR-Cl was able to permeate the human epidermis, and its penetration pattern was strongly influenced...

...) the highlights of my research (1960-1975) on skin permeation, and finally a reflection by an old-timer on more recent concepts. 28 02 2013 8 04 2013 29 7 2013 © 2013 S. Karger AG, Basel 2013 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication...

..., instructions or products referred to in the content or advertisements. Dermal drug delivery Nonivamide Pig ear skin Skin penetration Skin permeation Chronic itch is a widespread disease amongst the working population. In many cases, itching is a symptom of other diseases such as atopic...

...Daisuke Kobayashi; Shogo Kawabata; Kenji Sugibayashi; Yasunori Morimoto; Masayuki Kimura The in vitro/in vivo difference in enhanced skin permeation of nicardipine hydrochloride (NC) by simultaneous use of 1-menthol and ethanol (MEW system, 1-menthol:ethanol:water = 5:40:55) was investigated...

...L. Simonsen; A. Fullerton Atopic dermatitis (AD) skin has a defective barrier function as indicated by increased transepidermal water loss (TEWL). In order to test potential new formulations for AD, it was our aim to develop a skin permeation model simulating AD skin by inducing barrier impairment...

..., instructions or products referred to in the content or advertisements. Transdermal permeation Bioadhesive film Skin permeation Penetration enhancers Caffeine Skin Pharmacology and Physiology Original Paper Skin Pharmacol Physiol 2004;17:119 123 DOI: 10.1159/000077237 Bioadhesive Transdermal Film...

... on the skin is often based on knowledge of skin absorption and percutaneous permeation. Anatomical, physiological and biochemical similarities are cited and various uses of the pig as a model for man in the investigation of skin permeation are reviewed. Further, several isolated organ models are reviewed...