...F. Dreher; P. Walde; P.L. Luisi; P. Elsner Soybean lecithin microemulsion gels offer promising features for the possible use as matrices in transdermal therapeutic systems. In order to assess the skin irritancy potential of the gel, acute and cumulative irriation tests were performed in human...

... reaction. In vivo, different non-invasive parameters for the evaluation of skin irritation and irritant potential of compounds and their specific formulations have been introduced, such as epidermal barrier function, skin hydration, surface pH, lipid composition, skin colour and skin blood flow...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Skin surface pH Measurement Guidance Acid mantle pH gradient Natural moisturizing factor Stratum corneum Skin microflora Skin barrier Skin irritation Skin...

... tested for its ability to inhibit contact irritation. ECA (1% in vehicle) was highly effective in preventing ear edema due to topically applied skin irritants including arachidonic acid, capsaicin, lactic acid, phorbol myristate acetate, trans -retinoic acid, and sodium lauryl sulfate. ECA may be useful...