.../antioxidants, and inflammation in human dermal fibroblasts (HDF) subjected to oxidative stress. Methods: HDF were treated with H 2 O 2 in the presence or absence of 1–10 μM α-tocopherol. Cell viability, reactive oxygen species (ROS), NO release, and mitochondrial membrane potential were measured; glutathione...

..., the mechanism of mast cell activation is unclear. In this study, we examined the mechanism underlying the formation of dry skin induced by mast cells in arthritis that involves thymic stromal lymphopoietin (TSLP), neutrophils, reactive oxygen species (ROS), and glucocorticoids. Methods: Mice with DBA/1JJmsSlc...

...Leonhard Zastrow; Olivier Doucet; Louis Ferrero; Norbert Groth; Frank Klein; Dieter Kockott; Juergen Lademann Three evolutionary sources create ‘primary' reactive oxygen species (ROS) and ‘secondary' lipid oxygen species (LOS), forming the human body's ‘free radical ground state'. We present...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Antioxidants Carotenoids Free radicals Reactive oxygen species Skin...

... of action of tetracyclines seem to be most relevant for an effective treatment of acne and rosacea: inhibition of matrix metalloproteinases, downmodulation of cytokines, inhibition of cell movement and proliferation, inhibition of granuloma formation, inhibition of reactive oxygen species, nitric oxide...

...Jürgen Fuchs; Rainer Milbradt Reactive oxygen species play an important role in mediating skin inflammation, and antioxidants may provide protection. We investigated the anti-inflammatory activity of natural antioxidants, such as superoxide dismutase, catalase, trolox (a water-soluble tocopherol...

...J.R. Earl; M.C. Grootveld; D.R. Blake; C.J. Morris Opioid agents have been shown to protect against tissue damage caused by hypoxia/reperfusion, an event which has a significant reactive-oxygen-species (ROS) involvement. We have investigated the potential anti-inflammatory activity of three opioid...

... attention concerning their possible contribution to skin damage. A common biophysical answer for the different wavelengths of the sun spectrum can be found in the creation of excess free radicals – mainly reactive oxygen species (ROS). Thanks to electron spin resonance spectroscopy applied to skin biopsies...

..., instructions or products referred to in the content or advertisements. Reactive oxygen species UV light Leukocytes Antioxidants Skin Pharmacology andApplied Skin Physiology Skin Pharmacol Appl Skin Physiol 2002;15:367 373 Melatonin Suppresses Reactive Oxygen Species in UV-Irradiated Leukocytes More...

... radiation, much of the mutagenic and carcinogenic action of UVA radiation appears to be mediated through reactive oxygen species (ROS). Experiments have shown that UVA1 (340–400 nm) exposure induces SCC largely without the characteristic point mutations in p53 . Both UVB and UVA radiation can give rise...

... of Dermatology, University Münster, Münster, Germany Key Words UV radiation W DNA damage W Death receptor activation W Reactive oxygen species W Apoptosis Abstract Ultraviolet radiation (UV) induces a variety of biological effects which include the induction of programmed cell death. UV-induced apoptosis seems...

...Beate Tebbe Reactive oxygen species can cause harmful effects in keratinocytes and fibroblasts if antioxidative defence mechanisms are exhausted. Therefore, it seems to be reasonable to prove if oral supplementation with various nutrient antioxidants is useful in prevention or treatment of skin...