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Keywords: Proliferation
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Journal Articles
Skin Pharmacol Physiol (2021) 34 (5): 246–252.
Published Online: 29 April 2021
..., while ceramides (Cer) produced from SM on plasma membranes serve as a lipid mediator that regulates cell proliferation, differentiation, and apoptosis. In the skin, SM also is a precursor of Cer, an important constituent of epidermal permeability barrier. We investigated the role of epidermal SM...
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Skin Pharmacol Physiol (2013) 27 (1): 36–46.
Published Online: 06 August 2013
... Proliferation Tissue engineering Skin epithelium is a self-renewing tissue that functions as a barrier between the organism and its environment. This function is sustained in the epidermis by a tightly controlled equilibrium between cell proliferation and cell differentiation. Squamous differentiation...
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Skin Pharmacology (1997) 10 (2): 71–78.
Published Online: 01 April 2009
...Charles S. Harmon; Thomas D. Nevins; Janet Ducote; Diane Lutz We have used a series of bisindolylmaleimide selective pro-tein-kinase C (PKC) inhibitors to investigate the role of this enzyme in the regulation of cell proliferation in mouse hair follicle organ cultures. Mouse whisker follicles were...
Journal Articles
Skin Pharmacology (1997) 10 (4): 200–205.
Published Online: 01 April 2009
..., especially the fiavonoid fractions: quercetin, kaempfe-rol, sciadopitysin, ginkgetin, isoginkgetin, on the proliferation of normal human skin fibroblast in vitro measured by MTT (3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyl-tetrazolium bromide) assay and direct hemocytometer cell count. Furthermore, increased...
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Skin Pharmacology (1989) 2 (3): 175–179.
Published Online: 31 March 2009
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Ciclosporin H Epidermal keratinocytes Proliferation DNA synthesis Short Communication Skin Pharmacol 1989;2:175-179...
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Skin Pharmacology (1994) 7 (1-2): 55–60.
Published Online: 31 March 2009
... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Anagen hair Proliferation DNA flow cytometry Baldness, male pattern Hirsutism...
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Skin Pharmacology (1990) 3 (3): 149–156.
Published Online: 31 March 2009
...Janet A. Fairley; Peter D. Fung; Nancy M. Ewing Calmodulin, a major calcium-binding protein, is important in the regulation of cell proliferation. In human keratinocytes we found that culture confluence was accompanied by a decrease in calmodulin content. Ciclosporin A, 1–10 μg/ml, was found...
Journal Articles
Skin Pharmacology (1991) 4 (4): 278–285.
Published Online: 31 March 2009
... response together with the changes of LTB 4 levels in lesional skin biopsy specimens, and urinary leukotriene E 4 (LTE 4 ) excretion were evaluated. In addition, markers of inflammation, proliferation and keratinization were studied immunohistochemically. No change in clinical scores or lesional LTB 4...
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Skin Pharmacology (1992) 5 (1): 34–40.
Published Online: 31 March 2009
... of dithranol on epidermal proliferation, keratinization and inflammation was examined using immunohistochemistry. Punch biopsies from 6 volunteers who applied dithranol 0.5% in petrolatum were taken before application, after 48 and 96 h. Biopsies were processed for assessing epidermal proliferation by Ki67...
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Skin Pharmacology (1993) 6 (Suppl. 1): 24–34.
Published Online: 31 March 2009
...Gerard J. Gendimenico; James A. Mezick Retinoids exert profound pleiotropic effects in skin, affecting many aspects of cell differentiation and proliferation. For this reason, retinoids have prominent pharmacological effects on major skin cells (keratinocytes, dermal fibroblasts, melanocytes...
Journal Articles
Skin Pharmacol Physiol (2008) 21 (4): 227–234.
Published Online: 29 May 2008
... to explain. Methods: We analyzed the effect of all- trans retinoic acid (all- trans RA), 13- cis retinoic acid (13- cis RA), ergocalciferol and cholecalciferol in keratinocyte cultures established from adult donors, on the cell proliferation by means of [ 3 H]thymidine incorporation and apoptosis after...
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Skin Pharmacology and Applied Skin Physiology (2002) 15 (4): 262–269.
Published Online: 05 September 2002
... counteraction to this well-known irritation. Therefore, we studied the effect of single and repeated applications of dithranol on normal human skin. Besides a clinical evaluation, we studied aspects of epidermal proliferation, differentiation and inflammation. On day 2, after single dithranol challenge, we...
Journal Articles
Skin Pharmacology and Applied Skin Physiology (2000) 13 (3-4): 133–142.
Published Online: 02 June 2000
...-inhibiting activity of procyanidins and their hair-growing activity. Of the procyanidins, procyanidin B-2 and procyanidin C-1, which selectively inhibit protein kinase C, intensively promote hair epithelial cell proliferation in vitro and stimulate anagen induction in vivo. On the other hand, procyanidins...