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Keywords: Natural moisturizing factor
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Journal Articles

A Biomimetic Combination of Actives Enhances Skin Hydration and Barrier Function via Modulation of Gene Expression: Results of Two Double-Blind, Vehicle-Controlled Clinical Studies

Subject Area:
Dermatology , Pharmacology
Silke Altgilbers, Frank Rippke, Alexander Filbry, Stefanie Conzelmann, Jens-Peter Vietzke, Thorsten Burkhardt, Dörte Segger, Dennis Roggenkamp, Elke Grönniger
Journal: Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2022) 35 (2): 102–111.
https://doi.org/10.1159/000520009
Published Online: 07 October 2021
..., the most prevalent natural moisturizing factor (NMF), is currently considered the gold standard. Its efficacy can further be increased by combining urea with other NMF and skin barrier lipids (SBLs). Objective: We set out to evaluate physiological effects of a novel functional moisturizer containing 10...
View article titled, A Biomimetic Combination of Actives Enhances Skin Hydration and Barrier Function via Modulation of Gene Expression: Results of Two Double-Blind, Vehicle-Controlled Clinical Studies
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Journal Articles

Oral Supplementation of Collagen Peptides Improves Skin Hydration by Increasing the Natural Moisturizing Factor Content in the Stratum Corneum: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Subject Area:
Dermatology , Pharmacology
Miho Miyanaga, Taro Uchiyama, Akira Motoyama, Nobuhiko Ochiai, Osamu Ueda, Masashi Ogo
Journal: Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2021) 34 (3): 115–127.
https://doi.org/10.1159/000513988
Published Online: 26 March 2021
... and after 4, 8, and 12 weeks of treatment. The level of natural moisturizing factor (NMF) constituents in the stratum corneum (SC) was quantified before treatment and after 12 weeks of treatment. Results: Oral ingestion of CP increased the water content in the SC and epidermis and decreased TEWL...
View article titled, Oral Supplementation of Collagen Peptides Improves Skin Hydration by Increasing the <span class="search-highlight">Natural</span> <span class="search-highlight">Moisturizing</span> <span class="search-highlight">Factor</span> Content in the Stratum Corneum: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Open the PDF for Oral Supplementation of Collagen Peptides Improves Skin Hydration by Increasing the <span class="search-highlight">Natural</span> <span class="search-highlight">Moisturizing</span> <span class="search-highlight">Factor</span> Content in the Stratum Corneum: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial in another window
Journal Articles

In vivo Change of Keratin-Bound Molecules in the Human Stratum Corneum following Exposure to Ultraviolet Radiation

Subject Area:
Dermatology , Pharmacology
So Hyun Yoon, Jong Il Park, Ji Eun Lee, Cheol Hwan Myung, Jae Sung Hwang
Journal: Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2019) 32 (5): 254–264.
https://doi.org/10.1159/000501132
Published Online: 26 July 2019
... doses of UV radiation. Then, we examined erythema, the transepidermal water loss (TEWL), the water content, the natural moisturizing factor (NMF), and the lipids of the skin. Results: After UV irradiation, erythema and TEWL of the skin were both increased. The bound water content of the SC was also...
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Journal Articles

EEMCO Guidance for the in vivo Assessment of Skin Surface pH

Subject Area:
Dermatology , Pharmacology
J.L. Parra, M. Paye
Journal: Skin Pharmacology and Physiology
Skin Pharmacology and Applied Skin Physiology (2003) 16 (3): 188–202.
https://doi.org/10.1159/000069756
Published Online: 11 April 2003
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Skin surface pH Measurement Guidance Acid mantle pH gradient Natural moisturizing factor Stratum corneum Skin microflora Skin barrier Skin irritation Skin...
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