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Keywords: Keratinocytes
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Journal Articles
Skin Pharmacol Physiol (2021) 34 (2): 94–102.
Published Online: 17 March 2021
... such as 5-fluorouracil (5FU) induce intrinsic apoptosis. Objectives: To investigate the effects of TNFα on apoptosis in malignant and normal human keratinocytes. Methods: Human cutaneous squamous cell carcinoma (SCC) cell line SCC-13 and immortalized human keratinocytes HaCaT as well as primary normal human...
Journal Articles
Skin Pharmacol Physiol (2021) 34 (1): 30–37.
Published Online: 16 February 2021
... at baseline in keratinocytes may predict responsiveness to TGC in patients with CVD. Methods: In this retrospective cohort study, clinical and biological data of 25 women with a histological diagnosis of chronic vulvar eczema were analyzed. Randomization was done according to the responsiveness to TGC...
Journal Articles
Skin Pharmacol Physiol (2020) 33 (4): 189–197.
Published Online: 17 July 2020
... Keratinocytes Research Article Skin Pharmacol Physiol 2020;33:189 197 DOI: 10.1159/000509121 Received: January 6, 2020 Accepted: May 30, 2020 Published online: July 17, 2020 Epidermal Regeneration Induced by Comfrey Extract: A Study by Light and Electron Microscopy Dorothee Dähnhardt a Stephan Dähnhardt...
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Skin Pharmacol Physiol (2018) 31 (2): 74–86.
Published Online: 06 January 2018
... to in the content or advertisements. Vitamin D Skin Keratinocytes Psoriasis Atopic dermatitis The human skin acts as site of synthesis of vitamin D and also as target organ for the biologically active form of this vitamin. Vitamin D affects multiple functions in the skin ranging from keratinocyte...
Journal Articles
Skin Pharmacol Physiol (2018) 31 (1): 19–27.
Published Online: 08 November 2017
...Iga Hołyńska-Iwan; Inga Dziembowska; Paulina Smyk; Magdalena Lampka; Dorota Olszewska-Słonina Acute, adverse skin effects to capsaicin can be activated by inhibition of sodium transport not only in nociceptive neurons, but also in keratinocytes. The aim of the current study was to describe...
Journal Articles
Skin Pharmacol Physiol (2018) 31 (1): 10–18.
Published Online: 08 November 2017
... therapies, but medicinal plants are increasingly employed. Objective: To investigate the protective role of white willow bark (WWB) and 1,2-decanediol (DD) on the damage caused by lipopolysaccharides (LPS) on human adult keratinocytes (HaCaT). Methods: HaCaT were exposed to LPS alone or in association...
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Skin Pharmacology and Applied Skin Physiology (1997) 10 (5-6): 265–274.
Published Online: 01 April 2009
...Donald A. Vessey; Kyung-Hee Lee; Eva Lau Sixteen bile acids were tested at a concentration of 50 µ M for their effect on growth of preconfluent cultures of proliferating keratinocytes. Monohydroxy bile acids (3-Β-hydroxy-Δ5-cho-lenate and lithocholate) stopped the accumulation of protein...
Journal Articles
Journal Articles
Skin Pharmacology (1988) 1 (2): 106–114.
Published Online: 31 March 2009
... of forskolin (10 -7 M) were able to enhance isoproterenol’s effect under these conditions. Similarly, human keratinocyte cell cultures treated with phorbol esters and human psoriatic epidermis in vitro were both hyporesponsive to isoproterenol. Again, pretreatment of these samples with forskolin restored the Β...
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Journal Articles
Skin Pharmacology (1994) 7 (6): 307–315.
Published Online: 31 March 2009
...C. Theilig; A. Bernd; A. Ramirez-Bosca; F.F. Görmar; J. Bereiter-Hahn; B. Keller-Stanislawski; A.C. Sewell; N. Rietbrock; H. Holzmann Nicotine is rapidly taken up by human keratinocytes (HaCaT cells) and after 3 h the uptake is approximately 50% of maximum. Cotinine, a metabolite of nicotine...
Journal Articles
Skin Pharmacology (1994) 7 (6): 345–354.
Published Online: 31 March 2009
...F. Raffali; A. Rougier; R. Roguet The metabolism of xenobiotics by the epidermis can be studied in vitro by using keratinocyte cultures. We present a simple and rapid method for determining the activity of cytochrome P450-dependent enzymes (ethoxycoumarin-O-de-ethylase, ECOD, and ethoxyresorufm-O...
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Journal Articles
Skin Pharmacology (1995) 8 (3): 130–138.
Published Online: 31 March 2009
... kinase C (PKC) is considered to mediate cellular responses to other epidermal tumor promotors, we wished to investigate the relationship between BzPO and PKC in cultured human epidermal keratinocytes (NHEK). We assayed (a) direct effects of BzPO on PKC activity in a cell-free system using semipurified...
Journal Articles
Skin Pharmacology (1995) 8 (6): 309–318.
Published Online: 31 March 2009
...Yimin Xiong; Charles S. Harmon We have used fura-2/AM to investigate the effect of diazoxide on the cytosolic calcium concentration (Ca i ) in primary mouse keratinocyte cultures. Treatment of keratinocytes with 100 µ M diazoxide induced a transient peak in Ca i , followed by a sustained elevation...