... may lead to or contribute to irritation. Changes in skin surface inflammatory factors may provide further insight into this potential for irritation. The objective of this study was to evaluate the changes in epidermal properties and inflammatory mediators after 4 days of topical application of 2...

...S. Marrakchi; H.I. Maibach The particular sensitivity of the human face to care products prompted us to study irritation induced by sodium lauryl sulfate (SLS) in its various regions. We examined regional and age-related differences, correlating basal transepidermal water loss (TEWL...

...O.Q.J. Swinkels; M. Kucharekova; M. Prins; M.J.P. Gerritsen; P.G.M. van der Valk; P.C.M. van de Kerkhof Dithranol has been a mainstay in the treatment of psoriasis for more than 80 years. Although a safe approach, the irritation of the clinically uninvolved perilesional skin remains a major...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Ammonium lactate Urea Barrier function Irritation Stratum corneum hydration Original Research Article Skin Pharmacol Appl Skin Physiol...

...Valérie Zuang; Claudia Rona; Graeme Archer; Enzo Berardesca This study analyses the ability of four non-invasive techniques (laser Doppler velocimetry, evaporimetry, chromametry and corneometry) to discriminate between irritant and non-irritant products, when compared to appropriate controls...

... work showing a positive protective effect afforded by retinol against SLS. The combined effects of irritant compounds affecting the stratum corneum are complex. The precise reason for some of their biological consequences remains a conundrum. On balance, products such as SA and RA do not appear...