... permeation was evaluated from nanoemulsions containing OA or EU and an aqueous control solution through excised human full-thickness skin with hair follicles opened, blocked, or left untreated. Differential tape stripping was performed, followed by cyanoacrylate skin surface biopsies to determine the amount...

... and human skin. Optimized conditions were used to test the effect of SC damage and UV irradiation on the absorption of an UV filter combination present in a sunscreen. The bioavailability of the filters was extremely low regardless of the extent of skin damage, suggesting bioavailability would...

... Human Skin Pharmacol 1991;4:154-157 © 1991 S. Karger AG. Basel 1011-0283/91/0043-0154S2.75/0 Retinol Uptake and Metabolism to 3,4-Didehydroretinol in Human Kératinocytes at Various Stages of Differentiation Hans Tôrma, Anders Vahlquist Department of Dermatology, University Hospital, Linköping, Sweden...

... that these acids can enhance the permeation of various compounds across the skin. After topical and occlusive application as a solution in propylene glycol (PG) for 3 h on the volar arm of human subjects, SFA only caused a slight irritation and increase in TEWL. The diffusion lag times of HN were reduced...