...Mami Yokota; Yoshihiro Tokudome Background/Aims: Advanced glycation end products, which are linked to both aging and hyperglycemia, cause marked functional and structural alterations in human skin. Though it is well known that the metabolism of glucose is closely associated with that of fatty acid...

... of cholesterol. The more differentiated granular cells contain additional phospholipids and cholesterol and also contain significant proportions of glucosylceramides and ceramides. The stratum corneum contained mainly ceramides, cholesterol and fatty acids. Comparative studies demonstrated that porcine epidermis...

...Hanafi Tanojo; Esther Boelsma; Hans E. Junginger; Maria Ponec; Harry E. Boddé The in vivo effects of fatty acids on skin barrier function were assessed by measuring: (i) transepidermal water loss (TEWL), (ii) diffusion lag times for hexyl nicotinate (HN), and (iii) irritant skin response using...