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Keywords: Dithranol
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Journal Articles
Skin Pharmacology (1988) 1 (4): 259–264.
Published Online: 31 March 2009
...S. de Mare; N. Calis; G. den Hartog; P.E.J. van Erp; P.C.M. van de Kerkhof The relevance of salicylic acid in dithranol creams was evaluated in a double-blind study. Patients with chronic plaque psoriasis were treated using a short-contact schedule for dithranol on an outpatient basis. A left-right...
Journal Articles
Skin Pharmacology (1990) 3 (1): 1–20.
Published Online: 31 March 2009
...Lajos Kemény; Thomas Ruzicka; Otto Braun-Falco Dithranol is highly effective in the treatment of psoriasis. The drug inhibits keratinocyte hyperproliferation, granulocyte function and, in addition, may exert an immunosuppressive effect. Free radicals, histamine, eicosanoids and platelet-activating...
Journal Articles
Skin Pharmacology (1995) 8 (1-2): 1–24.
Published Online: 31 March 2009
... is discussed. In particular, compounds with diminished oxygen radical-generating properties have been developed, which may permit a separation of antipsoriatic and inflammatory effects. Some of the novel anthrone analogs which produced significantly less amounts of oxygen radicals than dithranol compared...
Journal Articles
Skin Pharmacology (1995) 8 (3): 119–129.
Published Online: 31 March 2009
...Reinhard Neubert; Wolfgang Wohlrab; Christina Bendas In this article, a new in vitro model system is presented with a multilayer membrane system serving as acceptor. Matrix-stabilized membranes are applied with dodecanol as lipid and collodion as matrix. Using the drug dithranol it was shown...
Journal Articles
Skin Pharmacology (1992) 5 (1): 25–28.
Published Online: 31 March 2009
... Anthralin inflammation Dithranol Histamine Antihistamine Terfenadine H 1 -receptor antagonist © 1992 S. Karger AG, Basel 1992 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any...
Journal Articles
Skin Pharmacology (1992) 5 (1): 41–48.
Published Online: 31 March 2009
... the whole scale length. In this model dithranol and retinoic acid dose-dependently increased orthokeratosis up to 75 and 79%, respectively. Beech tar, in a concentration of 5 % induced a 19 % increase in orthokeratosis. Morphometric quantification by image analysis of the conversion of parakeratotic...
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Skin Pharmacology and Applied Skin Physiology (2003) 16 (2): 69–83.
Published Online: 21 March 2003
... vitamin D 3 analogues and the retinoid tazarotene. To what extent, however, have we achieved developments which are in line with the needs as expressed by the patients? Improved efficacy has been realized by successful combinations of topical treatments. In particular, the combinations of dithranol...
Journal Articles
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Skin Pharmacology and Applied Skin Physiology (2003) 16 (1): 50–58.
Published Online: 05 February 2003
...T. Yamamoto; K. Nishioka Anthralin (dithranol) is frequently used for the treatment of psoriasis. However, the mode of action of anthralin has not been completely elucidated as yet. Recent findings suggest that psoriatic keratinocytes are resistant to the apoptotic process. In this study, we...
Journal Articles
Skin Pharmacology and Applied Skin Physiology (2002) 15 (6): 401–413.
Published Online: 16 December 2002
... and dithranol on differentiation and proliferation in the epidermis. Hairless rats were fed with a fat-free diet lacking linoleic acid. The EFAD condition was established within 8 weeks. In order to ensure that this condition had been established, several parameters were measured and observed, i.e. animal...
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Skin Pharmacology and Applied Skin Physiology (2000) 13 (5): 273–279.
Published Online: 11 August 2000
...M. Prins; O.Q.J. Swinkels; S.A. Bouwhuis; M.J. de Gast; Y. Bouwman-Boer; P.G.M. van der Valk; P.C.M. van de Kerkhof In the search for the ideal dithranol cream preparation for short-contact treatment of psoriasis, we investigated the clinical efficacy, side effects and patient appreciation of two...
Journal Articles
Skin Pharmacology and Applied Skin Physiology (2000) 13 (5): 285–291.
Published Online: 11 August 2000
... to the induction of orthokeratosis. The purpose of the present study was to investigate the effect of tazarotene, a novel, receptor-specific retinoid, by the mouse tail test in a direct comparison to dithranol representing a classical topical antipsoriatic compound. The tails of CFLP mice were treated...
Journal Articles
Skin Pharmacology and Applied Skin Physiology (2000) 13 (2): 128–132.
Published Online: 31 March 2000
... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. RNase P Ribozymes Dithranol...
Journal Articles