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Keywords: Cytochrome P450
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Journal Articles
Effect of Skin Metabolism on Dermal Delivery of Testosterone: Qualitative Assessment using a New Short-Term Skin Model
Available to Purchase
Journal:
Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2014) 27 (4): 188.
Published Online: 15 March 2014
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Alternative model Cytochrome P450 Dermal absorption Pig skin Transdermal drug delivery Testosterone metabolism...
Journal Articles
Measurement and Modulation of Cytochrome-P450-Dependent Enzyme Activity in Cultured Human Keratinocytes
Available to Purchase
Journal:
Skin Pharmacology and Physiology
Skin Pharmacology (1994) 7 (6): 345–354.
Published Online: 31 March 2009
...F. Raffali; A. Rougier; R. Roguet The metabolism of xenobiotics by the epidermis can be studied in vitro by using keratinocyte cultures. We present a simple and rapid method for determining the activity of cytochrome P450-dependent enzymes (ethoxycoumarin-O-de-ethylase, ECOD, and ethoxyresorufm-O...
Journal Articles
Effects of Human Recombinant Interferon-α2b on P450-Dependent Isozymes in Rat Liver and Skin
Available to Purchase
Journal:
Skin Pharmacology and Physiology
Skin Pharmacology (1995) 8 (3): 162–166.
Published Online: 31 March 2009
... Key Words Interferons Cytochrome P450 Liver Skin Monooxygenases Dedicated to Prof. Dr. H. Ippcn on the occasion of his 70th birthday. Abstract Adult female Wistar rats divided into two groups (6 animals each) were subcutaneously treated with 105 units/day recom binant human interferon-a2b (hrIFN-a2b...
Journal Articles
The Skin: Target Organ in Immunotoxicology of Small-Molecular-Weight Compounds
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Journal:
Skin Pharmacology and Physiology
Skin Pharmacology and Applied Skin Physiology (2001) 14 (6): 419–430.
Published Online: 03 October 2001
... of the skin. Examples include well-designed patch tests, assays involving antigen-presenting cells such as dendritic cells, but also T lymphocytes, basophiles or keratinocytes. Autoimmunity Immunosuppression Contact dermatitis Drug allergy Fragrances Cytochrome P450 © 2001 S. Karger AG, Basel...
Journal Articles
Molecular Biological Methods for Characterizing Drug-Metabolizing Enzymes in Hepatic and Extrahepatic Tissues
Available to Purchase
Journal:
Skin Pharmacology and Physiology
Skin Pharmacology and Applied Skin Physiology (1998) 11 (2): 61–69.
Published Online: 29 April 1998
...-Metabolizing Enzymes in Hepatic and Extrahepatic Tissues OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Key Words Extrahepatic drug metabolism Recombinant DNA Cytochrome P450 Pharmacokinetics OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Abstract Drug metabolism influences...