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Keywords: Cholesterol sulfate
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Journal Articles

Current Understanding of Skin Biology Pertinent to Skin Penetration: Skin Biochemistry

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Subject Area:
Dermatology , Pharmacology
P.W. Wertz
Journal: Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2013) 26 (4-6): 217–226.
https://doi.org/10.1159/000351949
Published Online: 29 July 2013
.... Second, it was established that the stratum corneum ceramides, cholesterol and fatty acids are present in an approximately 1:1:1 molar ratio with small amounts of cholesterol sulfate and cholesterol esters. Subsequent refinements to this composition have included the removal of triglycerides [ 15...
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Journal Articles

Acceleration of de novo Cholesterol Synthesis in the Epidermis Influences Desquamation of the Stratum Corneum in Aged Mice

Available to Purchase
Subject Area:
Dermatology , Pharmacology
A. Haratake, A. Komiya, T. Horikoshi, H. Uchiwa, S. Watanabe
Journal: Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2006) 19 (5): 275–282.
https://doi.org/10.1159/000093983
Published Online: 05 September 2006
... with aging. We found that the number of horny layers in murine SC increased with the decrease of desquamation in the outermost corneocytes associated with aging. The cholesterol content decreased and the cholesterol sulfate content increased in the horny layer with aging, which resulted in an increase...
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