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Keywords: Cholesterol
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Journal Articles
Evaluation of a Novel Skin Emollient Cream on Skin Lipidome and Lipid Organization
Available to PurchaseCarine Jacques, Caroline Dejean, Christian Klose, Emilie Leccia, Sandrine Bessou-Touya, Alain Delarue, Hélène Duplan
Journal:
Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2023) 36 (3): 125–139.
Published Online: 20 June 2023
...Carine Jacques; Caroline Dejean; Christian Klose; Emilie Leccia; Sandrine Bessou-Touya; Alain Delarue; Hélène Duplan Introduction: The stratum corneum (SC) matrix is composed of free fatty acids, cholesterol, and ceramides (CERs), which play a key role in the skin barrier function. Changes...
Journal Articles
Skin Diseases Associated with the Depletion of Stratum Corneum Lipids and Stratum Corneum Lipid Substitution Therapy
Available to Purchase
Journal:
Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2015) 28 (1): 42–55.
Published Online: 29 August 2014
... layer of the epidermis, the SC. The SC contains corneocytes that are embedded in a lipid matrix existing in the form of lipid bilayers. The lipid bilayers are formed mainly from ceramides, free fatty acids and cholesterol, constitute the only continuous pathway across the SC and are responsible...
Journal Articles
Current Understanding of Skin Biology Pertinent to Skin Penetration: Skin Biochemistry
Available to Purchase
Journal:
Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2013) 26 (4-6): 217–226.
Published Online: 29 July 2013
... of cholesterol. The more differentiated granular cells contain additional phospholipids and cholesterol and also contain significant proportions of glucosylceramides and ceramides. The stratum corneum contained mainly ceramides, cholesterol and fatty acids. Comparative studies demonstrated that porcine epidermis...
Journal Articles
Acceleration of de novo Cholesterol Synthesis in the Epidermis Influences Desquamation of the Stratum Corneum in Aged Mice
Available to Purchase
Journal:
Skin Pharmacology and Physiology
Skin Pharmacol Physiol (2006) 19 (5): 275–282.
Published Online: 05 September 2006
...A. Haratake; A. Komiya; T. Horikoshi; H. Uchiwa; S. Watanabe Cholesterol, a component of intercellular lipids, is important for stratum corneum (SC) homeostasis, including its barrier function and desquamation. However, cholesterologenesis in the epidermis decreases under basal conditions...
Journal Articles
Mass Spectrometric Examinations of Stratum corneum Lipid Models Exposed to Ultraviolet Irradiation
Available to Purchase
Journal:
Skin Pharmacology and Physiology
Skin Pharmacology and Applied Skin Physiology (2003) 16 (5): 291–304.
Published Online: 14 August 2003
... and cholesterol were found to be subject to oxidative changes caused by UV irradiation whereas the other lipids examined (dipalmitoylphosphatidylcholine, ceramide III and cholesterol sulphate) were stable to oxidative stress. Several lipid adducts were observed upon analysis of the liposomes. The composition...