... to in the content or advertisements. Xerosis cutis Dry skin Gene expression Urea Natural moisturizing factor Ceramide Xerosis cutis is a common skin condition. Many patients experience dry, scaly, and rough skin often associated with reduced elasticity and wrinkling. Further, erythema as well...

...Sung Ha Lim; Eun Jung Kim; Chung Hyuk Lee; Gi Hyun Park; Kang Min Yoo; Sung Ju Nam; Kyong-Oh Shin; Kyungho Park; Eung Ho Choi Introduction: The stratum corneum (SC) is a skin barrier that consists of corneocytes, intercellular lipids, and corneodesmosomes. Ceramides are composed of sphingoid bases...

..., it is unclear how LFPs affect human epidermal cell differentiation, ceramide (Cer), and amino acid production. Objective: The aim of this study was to determine the effects of LFPs on epidermal cell differentiation, by assessing amino acid and Cer production. Methods: A 3-dimensional cultured human epidermis...

... between them and their effects on the skin barrier in older people. This study aimed to compare the effect of a commercially available emollient containing 5% urea, ceramide NP and lactate (test emollient) to an alternative emollient without these additives (control emollient) on the properties...

... of cholesterol. The more differentiated granular cells contain additional phospholipids and cholesterol and also contain significant proportions of glucosylceramides and ceramides. The stratum corneum contained mainly ceramides, cholesterol and fatty acids. Comparative studies demonstrated that porcine epidermis...

...Y. Tokudome; M. Endo; F. Hashimoto Ceramide is an intercellular lipid of the stratum corneum and is one of the most important components of the epidermal permeability barrier. Glucosylceramide (GlcCer), a ceramide precursor, was applied to three-dimensional skin culture to regulate ceramide. GlcCer...

...T.N. Engelbrecht; B. Demé; B. Dobner; R.H.H. Neubert In order to elucidate the mode of action of the lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based on ceramide AP, cholesterol...

... was most effective at increasing its ceramide level. The diameters of the SPM-L in PBS were 102.7, 181.0, 224.0, and 380.1 nm. The diameters of the liposomes in the culture medium were 117.5, 199.2, 242.1, and 749.8 nm. The diameter of the small liposomes (<200 nm in diameter) did not change much...

... populations. In many cells ceramide is a mediator of proliferation inhibition and apoptosis, whereas sphingosine-1-phosphate acts more like a growth factor and reverses ceramide effects. In keratinocytes extracellular and intracellular ceramides play important roles. Extracellular ceramides are necessary...