...Shahnai Basharat; Syed Amir Gilani; Faiza Iftikhar; Mian Anjum Murtaza; Ayesha Basharat; Ahsan Sattar; Muhammad Mustafa Qamar; Muhammad Ali Background: Capsaicin, the main pungent ingredient in hot chili peppers, causes excitation of small sensory neurons. It also provides the basic pungent flavor...

... investigated the link between flare and itch using 3 models of itch. Methods: Skin provocations with histamine, capsaicin, and cowhage were performed in 31 subjects. Itch was quantified using the visual analog scale. Flare was assessed using laser speckle contrast imaging (LSCI) and digital photography...

...Johannes Wohlrab; Reinhard H.H. Neubert; Marie-Luise Heskamp; Julia Michael Objective: Epicutaneous application of capsaicin causes a long-lasting analgesic effect by binding to the membrane transient receptor potential vanilloid 1 (TRPV1) on mechanoheat-sensitive C and Aδ fibres, changing axonal...

...Peter Bjerring; Lars Arendt-Nielsen A new argon laser technique was introduced to evaluate the excitability of the free nerve endings in the skin following topical application of capsaicin. Short argon laser pulses can be perceived as distinct, painful pin pricks and the pain threshold can...

...Bruce Lynn Capsaicin selectively excites C-polymodal nociceptors in mammalian skin. In the rat, the only species so far studied in detail, a long-term desensitization of a subpopulation of C-polymodal nociceptors occurs after the initial excitation. After nerve treatment, permanent loss of some C...

...Joanna Wallengren; Duan Chen Capsaicin is used to investigate the role of peripheral sensory nerve fibers. In previous studies of rats treated by injection of capsaicin into the skin of the neck, ‘spontaneous’ lesions in the head and neck region were observed. In this study, the course...

...Elke Weisshaar; Beate Ziethen; Harald Gollnick Capsaicin (CAP) has been demonstrated to be an effective topical inhibitor of cutaneous vasodilatation, pain and pruritus induced by a variety of chemical and physical stimuli. In a previous study, we showed a significantly inhibitory effect of topical...

... 1999 Capsaicin Laser Doppler perfusion imaging Axon reflex Nicoboxil Nonivamide Finalgon Original Research Article Skin Pharmacol Appl Skin Physiol 1999;12:289 298 Received: Sept. 8, 1998 Accepted: April 19, 1999 The Effect of the Base on the Kinetics of Action of the Capsaicinoid...