... the efficacy of the herbal oil cream compared to a 0.05% calcipotriol-containing cream and to a vehicle cream, in 135 patients with mild to moderate plaque psoriasis with the change in Psoriasis Area and Severity Index (PASI) from baseline to week 12 as the primary endpoint. Results: EPR spectroscopy disclosed...

...Jean Lévy; Johannes Gassmüller; Gertrud Schröder; Heike Audring; Niels Sönnichsen In this study, we investigated the effect of calcipotriol, prednicarbate and clobetasol 17-propionate on skin thickness over a treatment period of 6 weeks. The study was conducted as a controlled, randomized, double...

...M. Bräutigam; H. Hübner; P. Rach; R. Thieroff-Ekerdt Topical application of calcitriol or its analogs is a new approach for treating psoriasis, but may be limited by systemic calcitropic effects. Calcipotriol (MC 903) is a novel calcitriol analog with low calcitropic potency after systemic...

...E. Bangha; P. Elsner The antipsoriatic effects of two topical antipsoriatic agents, betamethasone valerate (Betnovate®) and calcipotriol (Dai-vonex®), and a pure nanocolloid gel were assessed in 10 patients with chronic plaque-type psoriasis in a modified psoriasis plaque test. Three noninvasive...

... in psoriasis, although several reports suggest that vitamin D 3 is less effective in reducing the inflammatory changes compared to its potent effect on keratinocyte growth and differentiation. The aim of the present study was to compare and contrast the effects of the vitamin D 3 analogue calcipotriol...

...Monika Jensen; Lotte Groth; Gunhild Hølmer; Harald S. Hansen; Ann Fullerton The objective of this study was to establish essential fatty acid deficiency (EFAD) in hairless rats and investigate the potential of this model as a psoriasis screening model by testing the effects of calcipotriol...