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Keywords: Body burden
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Journal Articles
Journal:
Skin Pharmacology and Physiology
Skin Pharmacology (1991) 4 (4): 235–245.
Published Online: 31 March 2009
... of dexamethasone and hydrocortisone desorbed. A topical delivery system was developed with and without TC and was evaluated in vivo using the rat as an animal model for hydrocortisone accumulation after multiple dosing. The systemic body burden was reduced by 70% and skin retention of hydrocortisone was incresed...
